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Evaluation of the Living Donor

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Diagnostic and Interventional Radiology in Liver Transplantation

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

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Abstract

Living related donation is a well-established practice in pediatric liver transplantation, with more than 700 procedures having been performed world-wide so far (Anonymous 1997; Malago et al. 1997). Initially developed to alleviate the shortage of small grafts for children, living related liver transplantation (LRLT) is now a highly effective therapy for pediatric patients. It offers several advantages in comparison to transplantation of a cadaveric graft. Most importantly, living donation allows optimal timing of transplantation by reduction or even elimination of waiting time for a graft (BROELSCH et al. 1994). The elective timing allows transplantation to be performed in children before their medical condition deteriorates and thus reduces the risk of the transplant procedure. In addition, this entails a substantial psychological relief for both the patient and the family (Singer et al. 1990). Second, the graft quality of a living donated organ is in general excellent. The graft is procured from a healthy donor after careful medical screening under controlled, elective circumstances. Thus, a prolonged cold ischemic time can be avoided, reducing the risk of primary nonfunction of the graft (Broelsch et al. 1991; Emond et al. 1993). Third, immunological benefits involved with donation of an organ from a close blood relative are anticipated, although as yet this has not been clearly documented (Emond 1993).

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Authors and Affiliations

  1. Medizinische Kernklinik und Poliklinik, Universitäts-krankenhaus Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany

    M. Sterneck MD

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  1. M. Sterneck MD
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Editors and Affiliations

  1. Klinik und Poliklinik für Radiologie, Universitätsklinikum Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany

    E. Bücheler MD (Professor) (Professor)

  2. Departments of Radiology and Nuclear Medicine, University Hospital Bergmannsheil Bochum, Bürkle-de-la-Camp-Platz 1, 44789, Bochum, Germany

    V. Nicolas MD (Professor) (Professor)

  3. Klinik und Poliklinik für Allgemeinchirurgie und Transplantationschirurgie, Universitätsklinik Essen, Hufelandstrasse 55, 45122, Essen, Germany

    C. E. Broelsch MD, FACS (Professor, Director) (Professor, Director)

  4. Klinik und Polyklinik für Chirurgie, Universitätsklinikum Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany

    X. Rogiers MD

  5. Klinik und Polyklinik für Radiologie, Universitätsklinikum Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany

    G. Krupski MD, PhD (Professor) (Professor)

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© 2003 Springer-Verlag Berlin Heidelberg

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Sterneck, M. (2003). Evaluation of the Living Donor. In: Bücheler, E., Nicolas, V., Broelsch, C.E., Rogiers, X., Krupski, G. (eds) Diagnostic and Interventional Radiology in Liver Transplantation. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-55955-6_5

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  • DOI: https://doi.org/10.1007/978-3-642-55955-6_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-62950-1

  • Online ISBN: 978-3-642-55955-6

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