Abstract
Steep concentration gradients of the chromatographical separation process lead to discretisation errors. Different approaches to reduce these inaccuracies are applied and compared. The following methods have been investigated:
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Local grid refinement
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Application of different discretisation schemes
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Moving mesh
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Relation of the discretisation with respect to time and space
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Weighting of the differential equation system
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References
(Aug. 1996) FLUENT Users’s Guide. Fluent Inc., London
Seidel-Morgenstern, A. (1995) Mathematische Modellierung der präparativen Flüssigchromatographie, Deutscher Universitätsverlag DUV, Wiesbaden, ISBN 3–8244–3–8244
Klein, A. (1999) Parameterstudien zur hydrodynamischen Optimierung von chromatographischen Säulen, Studienarbeit TU-Berlin, 35–43
Coulson, J. M., Richerson J. F. (1991) Chemical Engineering, Butterworth-Heinemann, Oxfort, ISBN 0–7506–0–7506
Laiblin T., Arlt W., Wozny G., Lisso M., Boysen H., (2000) Conference Proceedings, Spica, Zürich
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Boysen, H., Wozny, G., Lisso, M., Arlt, W., Laiblin, T. (2002). Simulation of High Pressure Liquid Chromatography (HPLC) Columns with CFD. In: Breuer, M., Durst, F., Zenger, C. (eds) High Performance Scientific And Engineering Computing. Lecture Notes in Computational Science and Engineering, vol 21. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-55919-8_5
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DOI: https://doi.org/10.1007/978-3-642-55919-8_5
Publisher Name: Springer, Berlin, Heidelberg
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