Skip to main content

Portale Hypertension

  • Chapter
Klinische Hepatologie
  • 104 Accesses

Zusammenfassung

Der normale Druck in der Pfortader liegt zwischen 3 und 6 mm Hg. Die portale Hypertension ist als dauerhafte Erhöhung des Pfortaderdrucks auf Werte ≥ 7 mm Hg und/oder des transhepatischen Druckgradienten zwischen geblocktem Lebervenenverschlussdruck und dem Druck im zentralen Venensystem des systemischen Kreislaufs auf Werte ≥ 5 mm Hg definiert. Die Erhöhung des portalvenösen Gradienten auf Werte < 10 – 12 mm Hg, Varizen, Varizenblutung und/oder Aszites zeigen die klinisch signifikante portale Hypertension an.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 119.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 159.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Aithal GP, Alabdi BJ, Rose JDG et al. (1999) Portal hypertension secondary to arterio-portal fistulae: two unusual cases. Liver 19: 343–347

    Article  PubMed  CAS  Google Scholar 

  • Bataller R, Ginès P, Nicohis M et al. (2000) Angiotensin II induces contraction and proliferation of human hepatic stellate cells. Gastroenterology 118: 1149–1156

    Article  PubMed  CAS  Google Scholar 

  • Cho JJ, Hocher B, Herbst H et al. (2000) An oral endothelin-A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis. Gastroenterology 118: 1169–1178

    Article  PubMed  CAS  Google Scholar 

  • De Franchis R (2000) Updating consensus in portal hypertension: report of the Baveno III consensus workshop on definitions, methodology and therapeutic strategies in portal hypertension. J Hepatol 33: 846–852

    Article  PubMed  Google Scholar 

  • LaBreque DR (1997) Portal hypertension. Clin Liver Dis 1: 1–24

    Article  Google Scholar 

  • Lebrec D, Moreau R (2001) Pathogenesis of portal hypertension. Eur J Gastroenterol Hepatol 13: 309–311

    Article  PubMed  CAS  Google Scholar 

  • Moriyasu F, Ban N, Nishida O et al. (1988) Clinical application of an ultrasonic duplex system in the quantitative measurement of portal blood flow. J Clin Ultrasound 14: 579–588

    Article  Google Scholar 

  • Pateron D, Tazi KA, Sogni P et al. (2000) Role of aortic nitric oxide synthase 3 (eNOS) in the systemic vasodilation of portal hypertension. Gastroenterology 119: 196–200

    Article  PubMed  CAS  Google Scholar 

  • Rockey DC (1997) The cellular pathogenesis of portal hypertension: stellate cell contractility, endothelin and nitric oxide. Hepatology 25: 2–5

    Article  PubMed  CAS  Google Scholar 

  • Rockey DC, Chung JJ (1998) Reduced nitric oxide production by endothelial cells in cirrhotic rat liver: endothelial dysfunction in portal hypertension. Gastroenterology 114: 344–351

    Article  PubMed  CAS  Google Scholar 

  • Sabba C, Merkel C, Zoli M et al. (1995) Interobserver and interequipment variability of echo-doppler examination of the portal vein: effect of a cooperative training program. Hepatology 21: 428–433

    PubMed  CAS  Google Scholar 

  • Shah V, Haddad FG, Garda-Cardena G et al. (1997) Liver sinusoidal endothelial cells are responsible for nitric oxide modulation of resistance in the hepatic sinusoids. J Clin Invest 100:2923–2930

    Article  Google Scholar 

  • Shah V, Garda-Cardena G, Sessa WC (1998) The hepatic circulation in health and disease: report of a single-topic symposium. Hepatology 27: 279–288

    Article  PubMed  CAS  Google Scholar 

  • Wanless JR (1997) Noncirrhotic portal hypertension: recent concepts. Progr Liver Dis 14: 265–278

    Google Scholar 

  • Wiest R, Lock G, Schölmerich J (2000) Portale Hypertension. Internist 41: 1077–1095

    Article  PubMed  CAS  Google Scholar 

Download references

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2003 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Dancygier, H., Weber, C. (2003). Portale Hypertension. In: Klinische Hepatologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-55902-0_18

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-55902-0_18

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-67559-4

  • Online ISBN: 978-3-642-55902-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics