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Biologische Strahlenwirkungen

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Handbuch diagnostische Radiologie

Part of the book series: Handbuch diagnostische Radiologie ((HDR))

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Zusammenfassung

In allen lebenden Organismen von einfachen Bakterien bis zu Säugerzellen hat sich die Fähigkeit entwickelt, DNA-Schäden zu erkennen und zu reparieren (Übersicht bei Friedberg et al. 1995). Diese Schäden können nicht nur durch externe Einflüsse wie Röntgen-, UV-Bestrahlung und Einwirkung von Chemikalien, sondern in groβem Umfang auch durch endogene Prozesse entstehen. V.a. durch den oxidativen Metabolismus werden in jeder Zelle täglich viele tausend DNA-Schäden erzeugt. Die Fähigkeit einer Zelle, DNA-Schäden zu erkennen und zu beseitigen, ist somit eine wesentliche Voraussetzung für die Stabilität des Genoms.

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Authors and Affiliations

  1. Institut für Strahlenbiologie, GSF-Forschungszentrum Neuherberg, Postfach 11 29, 85758, Oberschleiβheim, Germany

    M. Bauchinger

  2. Universitätsklinikum Hamburg-Eppendorf, Abt. für Strahlentherapie, Martinistr. 52, 20246, Hamburg, Germany

    J. Dahm-Daphi & U. Kasten

  3. Universitätsklinikum Hamburg-Eppendorf, Institut für Biophysik und Strahlenbiologie, Martinistr. 52, 20246, Hamburg, Germany

    E. Dikomey & H. Jung

  4. Sektion für Strahlenbiologie und Molekulare Umweltforschung, Universitätsklinikum Tübingen, Röntgenweg 11, 72076, Tübingen, Germany

    H. Dittmann & M. Rodemann

  5. Technische Universität Dresden Klinik u. Poliklinik für Strahlentherapie u. Radioonkologie, Fetscherstr. 74, 01307, Dresden, Germany

    T. Herrmann

  6. Institut für Strahlenhygiene des Bundesamtes für Strahlenschutz, Ingolstädter Landstr. 1, 85764, Oberschleiβheim, Germany

    G. Stephan

  7. Universitätsklinikum Essen, Institut für Wissenschaft und Ethik, Robert-Koch-Str. 9-11, 45122, Essen, Germany

    C. Streffer

  8. Dept. Radiat. Biology, St. Bartholomew’s Med. Col., Charterhouse Square, EC1 M 6BQ, GB-London, UK

    K.-R. Trott

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  1. M. Bauchinger
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  6. H. Jung
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  7. U. Kasten
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  9. G. Stephan
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  10. C. Streffer
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  11. K.-R. Trott
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Editors and Affiliations

  1. Institut für Med. Physik, Klinikum Nürnberg, Prof.-Ernst-Nathan-Str. 1, 90340, Nürnberg, Deutschland

    Th. Schmidt

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Bauchinger, M. et al. (2003). Biologische Strahlenwirkungen. In: Schmidt, T. (eds) Handbuch diagnostische Radiologie. Handbuch diagnostische Radiologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-55825-2_3

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  • DOI: https://doi.org/10.1007/978-3-642-55825-2_3

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