HP1 Complexes and Heterochromatin Assembly

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 274)


Since its discovery almost two decades ago, heterochromatin protein 1 (HP1) has emerged as a major player in the transcriptional regulation of both heterochromatic and euchromatic genes as well as the mechanics of chromosome segregation and the functional and structural organization of the interphase nucleus. Recent years have brought the identification of a myriad of HP1-interacting proteins. Each of these is discussed in relationship to its role in heterochromatin assembly and HP1 function. The breadth of functions represented by HP1-interacting proteins testifies to its pivotal role in the daily operations of the nucleus.


Fission Yeast Origin Recognition Complex Position Effect Variegation Chromatin Assembly Factor Heterochromatin Assembly 
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© Springer-Verlag Berlin Heidelberg 2003

Authors and Affiliations

  1. 1.School of Biological SciencesUniversity of KentuckyLexingtonUSA

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