Skip to main content
SpringerLink
Log in

Picoliter Droplets for Single-Particle and Single-Molecule Imaging

  • Chapter
Single Organic Nanoparticles

Part of the book series: NanoScience and Technology ((NANO))

  • 486 Accesses

Abstract

Generation of subnanoliter droplets [1–16] is a fundamental technique in modern analytical chemistry. The current methodology of generating droplets can be divided into three types based on the generation technique: vibrating orifice, extrusion, and electrospray, as depicted in Fig. 23.1.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. R.E. Russo, R. Withnell, G.M. Hieftje: Appl. Spectrosc. 35, 531 (1988)

    Article  Google Scholar 

  2. A.G. Childers, G.M. Hieftje: Appl. Spectrosc. 40, 531 (1986)

    Article  Google Scholar 

  3. D.B. Hager, N.J. Dovichi: Anal. Chem. 66, 1593 (1994)

    Article  CAS  Google Scholar 

  4. D.B. Hager, N.J. Dovichi, J. Klassen, P. Kebarle: Anal. Chem. 66, 3944 (1994)

    Article  CAS  Google Scholar 

  5. J.B. French, B. Etkin, R. Jong: Anal. Chem. 66, 685 (1994)

    Article  CAS  Google Scholar 

  6. H.B. Lin, J.D. Eversole, A.J. Campillo: Rev. Sci. Instrum. 61, 1018 (1990)

    Article  CAS  Google Scholar 

  7. W.B. Whitten, J.M. Ramsey, S. Arnold, B.V. Bronk: Anal. Chem. 63, 1027 (1991)

    Article  CAS  Google Scholar 

  8. K.C. Ng, W.B. Whitten, S. Arnold, J.M. Ramsey: Anal. Chem. 64, 2914 (1992)

    Article  CAS  Google Scholar 

  9. M.D. Barnes, K.C. Ng, W.B. Whitten, J.M. Ramsey: Anal. Chem. 65, 2360 (1993)

    Article  CAS  Google Scholar 

  10. M.D. Barnes, K.C. Ng, K.P. McNamara, C.Y. Kung, J.M. Ramsey, S.C. Hill: Cytometry 36, 169 (1999)

    Article  CAS  Google Scholar 

  11. A.V. Lemmo, J.T. Fisher, H.M. Geysen, D.J. Rose: Anal. Chem. 69, 543 (1997)

    Article  CAS  Google Scholar 

  12. K. Hosokawa, T. Fujii, I. Endo: Anal. Chem. 71, 4781 (1999)

    Article  CAS  Google Scholar 

  13. D.J. Graves, H.J. Su, S.E. Mckenzie, S. Surrey, P. Fortina: Anal. Chem. 70, 5085 (1998)

    Article  CAS  Google Scholar 

  14. P. Onnerfjord, J. Nilsson, L. Wallman, T. Laurell, G. Marko-Varga: Anal. Chem. 70, 4755 (1998)

    Article  CAS  Google Scholar 

  15. P. Kebarle, Y. Ho: On the Mechanism of Electrospray Mass Spectrometry. In: Electrospray Ionization Mass Spectrometry, ed. by R.C. Cole (John Wiley & Sons, New York 1997) pp. 1-63

    Google Scholar 

  16. L.C. Mountford, R.A. Smith, M.H.R. Hutchinson: Rev. Sci. Instrum. 69, 3780 (1998) ai17._Generation of 2-pL droplets was reported in 2880-dpi inkjet printing using piezoelectric technique (http://www.i-love-epson.co.jp/products/ hi-kaku/color.htm)

    Article  CAS  Google Scholar 

  17. O. Yogi, T. Kawakami, M. Yamauchi, J.Y. Ye, M. Ishikawa: Anal. Chem. 73, 1896 (2001)

    Article  CAS  Google Scholar 

  18. M. Cloupeau, B. Prunet-Foch: J. Aerosol Sci. 25, 1021 (1994)

    Article  CAS  Google Scholar 

  19. M. Ishikawa, O. Yogi, J.Y. Ye, T. Yasuda, Y. Maruyama: Anal. Chem. 70, 5198 (1998)

    Article  CAS  Google Scholar 

  20. I.G. Loscertales, A. Barrero, I. Guerrero, R. Cortijo, M. Marquez, A.M. GañánCalvo: Science 295, 1695 (2002)

    Article  CAS  Google Scholar 

  21. G. MacBeath and S.L. Schreiber: Science 289, 1760 (2000)

    CAS  Google Scholar 

  22. H. Sirringhaus, T. Kawase, R.H. Friend, T. Shimoda, M. Inbasekaran, W. Wu, E.P. Woo: Science 290, 2123 (2000)

    Article  CAS  Google Scholar 

Download references

Authors
  1. M. Ishikawa
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Applied Physics, Osaka University, 2-1 Yamada-Oka Suita 565-0871, Japan

    Hiroshi Masuhara

  2. Institute of Multidisciplinary Research for Advanced Materials (IMRAM), Tohoku University, Katahira 2-1-1, Aoba-ku, Sendai, 980-8577, Japan

    Hachiro Nakanishi

  3. Research Institute for Electronic Science, Hokkaido University, Sapporo, 060-0812, Japan

    Keiji Sasaki

Rights and permissions

Reprints and permissions

Copyright information

© 2003 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Ishikawa, M. (2003). Picoliter Droplets for Single-Particle and Single-Molecule Imaging. In: Masuhara, H., Nakanishi, H., Sasaki, K. (eds) Single Organic Nanoparticles. NanoScience and Technology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-55545-9_23

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-55545-9_23

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-62429-2

  • Online ISBN: 978-3-642-55545-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation