Abstract
Focal liver lesions are present in more than 5 % of the population and are often detected incidentally when an imaging study is performed for another reason (Table 8.1). In 40 % of cases, it is not possible to categorize such incidental lesions adequately by imaging (Strobel and Bernatik 2006). Liver lesions are especially challenging for the radiologist interpreting whole-body screening MRI studies, which typically only include non-contrast-enhanced pulse sequences. With unenhanced MR images, only a crude characterization of focal liver lesions is possible.
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References
Aghdassi AA, Mayerle J, Kraft M, Sielenkaemper AW, Heidecke CD, Lerch MM (2006) Pancreatic pseudocysts -when and how to treat? HPB (Oxford) 8:432–441
Angulo P (2002) Nonalcoholic fatty liver disease. N Engl J Med 346:1221–1231
Assisi A, Papotzi R, Negri P, Bordoli M, Nardone A, Nespoli A (1998) Acute cholecystitis and gallbladder neoplasms: the experience of 2215 cases. G Chir 19:391–394
Aubé C, Delorme B, Yzet T, Burtin P, Lebigot J, Pessaux P, Gondry-Jouet C, Boyer J, Caron C (2005) MR cholangiopancreatography versus endoscopic sonography in suspected common bile duct lithiasis: a prospective, comparative study. AJR Am J Roentgenol 184:55–62
Balthazar EJ (2002) Acute pancreatitis: assessment of severity with clinical and CT evaluation. Radiology 223:603–613
Banas B, Mussack T, Pfeifer KJ, Wörnle M, Schmid H (2003) Große Nebennierenzysten: Zunehmende Inzidenz einer häufig malignen Erkrankung. Dtsch Arztebl 100:A-921
Bizer LS, Liebling RW, Delany HM, Gliedmann ML (1981) Small bowel obstruction. Surgery 89:407–413
Blum HE (1995) Variants of hepatitis B, C and D viruses: molecular biology and clinical significance. Digestion 56:85–95
Bollschweiler E, Moenig S, Hoelscher AH (2001) Lymphknotenmetastasierung – Kann man sie vorhersagen? Der Onkologe 7:604–609
Buetow PC, Pantongrag-Brown L, Buck JL, Ros PR, Goodman ZD (1996) Focal nodular hyperplasia of the liver: radiologic-pathologic correlation. Radiographics 16:369–388
Cappeliez O, Delhaye M, Deviere J, Le Moine O, Metens T, Nicaise N, Cremer M, Stryuven J, Matos C (2000) Chronic pancreatitis: evaluation of pancreatic exocrine function with MR pancreatography after secretin stimulation. Radiology 215:358–564
Caremani M, Vincenti A, Benci A, Sassoli S, Tacconi D (1993) Ecographic epidemiology of non-parasitic hepatic cysts. J Clin Ultrasound 21:115–118
Carrim ZI, Murchison JT (2003) The prevalence of simple renal and hepatic cysts detected by spiral computed tomography. Clin Radiol 58:626–629
Cherqui D, Rahmouni A, Charlotte F, Boulahdour H, Métreau JM, Meignan M, Fagniez PL, Zafrani ES, Mathieu D, Dhumeaux D (1995) Management of focal nodular hyperplasia and hepatocellular adenoma in young women: a series of 41 patients with clinical, radiological and pathological correlations. Hepatology 22:1674–1681
Chintapalli KN, Chopra S, Ghiatas AA, Esola CC, Fields SF, Dodd GD (1999) Diverticulitis versus colon cancer: differentiation with helical CT findings. Radiology 210:429–435
Chuang WY, Chen TC, Hsu HL, Lee WC, Jeng LB, Huang SF (2002) Liver cell adenoma with concomitant hepatocellular carcinoma: report of two cases. J Formos Med Assoc 101:798–802
de Porto AP, Lammers AJ, Bennink RJ, ten Berge IJ, Speelman P, Hoekstra JB (2010) Assessment of splenic function. Eur J Clin Microbiol Infect Dis 29:1465–1473
de Wilt JH, de Man RA, Laméris JS, Zondervan PE, Tilanus HW, IJzermans JN (1998) Hepatocellular adenoma in 20 patients; recommendations for treatment. Ned Tijdschr Geneeskd 142:2459–2463
Dröge C, Löhlein D, Hausamen TU (1996) Acute intrahepatic bleeding in a male patient with focal nodular hyperplasia. Dtsch Med Wochenschr 121:902–905
Dunnick NR, Korobkin M, Francis I (1996) Adrenal radiology: distinguishing benign from malignant adrenal masses. AJR Am J Roentgenol 167:861–867
Eisenberg RL, Margulis AR (1991) Brief history of gastrointestinal radiology. Radiographics 11:121–132
Escourrou J, Cordova JA, Lazorthes F, Frexinos J, Ribet A (1984) Early and late complications after endoscopic sphincterotomy for biliary lithiasis with and without the gallbladder in situ. Gut 25:598–602
Fernandez-del Castillo C, Targarona J, Thayer SP, Rattner DW, Brugge WR, Warshaw AL (2003) Incidental pancreatic cysts: clinicopathologic characteristics and comparison with symptomatic patients. Arch Surg 138:427–434
St Pierre, TG et al (2005) Noninvasive measurement and imaging of liver iron concentrations using proton magnetic resonance. Blood 105:855–861. Ferriscan, available under www.ferriscan.com
Fukuya T, Honda H, Hayashi T, Kaneko K, Tatesho Y, Ro T, Maehara Y, Tanaka M, Tsuneyoshi M, Masuda K (1995) Lymph node metastases: efficacy for detection with helical CT in patients with gastric cancer. Radiology 197:705–711
Gaines PA, Sampson MA (1989) The prevalence and characterization of simple hepatic cysts by ultrasound examination. Br J Radiol 62:335–337
Gandon Y, Olivié D, Guyader D, Aubé C, Oberti F, Sebille V, Deugnier Y (2004) Non-invasive assessment of hepatic iron stores by MRI. Lancet 363:357–362
Glazer HS, Weyman PJ, Sagel SS, Levitt RG, McClennan BL (1982) Nonfunctioning adrenal masses: incidental discovery on computed tomography. AJR Am J Roentgenol 139:81–85
Grebe P, Schild H, Kreitner KF, Ferber A (1994) The differentiation between benign and malignant liver lesions by unenhanced MRI. Rofo 161:412–416
Hodges FV, Ellis FR (1958) Cystic lesions of the adrenal gland. Arch Pathol 66:53–58
Holzapfel K, Eiber MJ, Fingerle AA, Bruegel M, Rummeny EJ, Gaa J (2012) Detection, classification, and characterization of focal liver lesions: Value of diffusion-weighted MR imaging, gadoxetic acid-enhanced MR imaging and the combination of both methods. 37(1):74–82, doi: 10.1007/s00261-011-9758-1
Ito K, Mitchell DG, Honjo K, Fujita T, Uchisako H, Matsumoto T, Matsunaga N, Honma Y, Yamakawa K (1997) MR imaging of acquired abnormalities of the spleen. AJR Am J Roentgenol 168:697–702
Kew MC (1998) Hepatitis viruses and hepatocellular carcinoma. Res Virol 149:257–262
Kim HC, Park SJ, Park SI, Park SH, Kim HJ, Shin HC, Bae WK, Kim IY, Lee HK (2005) Multislice CT cholangiography using thin-slab minimum intensity projection and multiplanar reformation in the evaluation of patients with suspected biliary obstruction: preliminary experience. Clin Imaging 29:46–54
Kojima S, Watanabe N, Numata M, Ogawa T, Matsuzaki S (2003) Increase in the prevalence of fatty liver in Japan over the past 12 years: analysis of clinical background. J Gastroenterol 38:954–961
Kreft B, Sommer T, Vahlensieck M, Seewald S, Vetter H, Schild H (1995) Turbo-spin-echo (TSE) sequences with selective fat suppression (SPIR) compared with chemical shift sequences in MRI for differentiation of adrenal tumors. Spectral presaturation by inversion recovery. Rofo 162:311–318
Labruzzo C, Haritopoulos KN, El Tayar AR, Hakim S (2002) Posttraumatic cyst of the spleen: a case report and review of the literature. Int Surg 87:152–156
Lankisch PG, Struckmann K, Assmus C, Lehnick D, Maisonneuve P, Lowenfels AB (2001) Do we need a computed tomography examination in all patients with acute pancreatitis within 72 h after admission to hospital for the detection of pancreatic necrosis? Scand J Gastroenterol 36:432–436
Lee DH, Ko YT (1998) The role of 3D spiral CT in early gastric carcinoma. J Comput Assist Tomogr 22:709–713
Levy AD, Murakata LA, Jr Rohrmann CA (2001) Gallbladder carcinoma: radiologic-pathologic correlation. Radiographics 21:295–314
Lieb JG, Draganov PV (2007) Early successes and late failures in the prevention of postendoscopic retrograde cholangiopancreatography pancreatitis. World J Gastroenterol 13:3567–3574
Morgan DE, Logan K, Baron TH et al (1999) Pancreas divisum: implications for diagnostic and therapeutic pancreatography. AJR Am J Roentgenol 173:193–198
Moulton JS (1988) CT of the adrenal glands. Semin Roentgenol 23:288–303
Neubrand M, Sackmann M, Caspary W, Feussner H, Schild H, Lauchart W, Schildberg FW, Reiser M, Classen M, Paumgartner G, Sauerbruch T (2000) Guidelines by the German Society of Digestive and Metabolic Diseases for treatment of gallstones. German Society of Digestive and Metabolic Diseases. Z Gastroenterol 38:449–468
NIH state-of-the-science statement on management of the clinically inapparent adrenal mass (“incidentaloma”) (2002). NIH Consens State Sci Statements. 4–6;19(2):1–25
Nufer M, Stuckmann G, Decurtins M (1999) Benign liver tumors: diagnosis and therapy- a review. Schweiz Med Wochenschr 129:1257–1264
Oi H, Matsushita M, Murakami T, Nakamura H (1997) Dynamic MR imaging for extraserosal invasion of advanced gastric cancer. Abdom Imaging 22:35–40
Pickhardt PJ, Asher DB (2003) Wall thickening of the gastric antrum as a normal finding: multidetector CT with cadaveric comparison. AJR Am J Roentgenol 181:973–979
Rabushka LS, Kawashima A, Fishman EK (1994) Imaging of the spleen. CT with supplemental MR examinations. Radiographics 14:307–332
Robbins FG, Yellin AE, Lingua RW, Craig JR, Turrill F, Mikkelsen WP (1978) Splenic epidermoid cysts. Ann Surg 187:231–235
Robertson F, Leander P, Ekberg 0 (2001) Radiology of the spleen. Eur Radiol 11:80–95
Robson KJH, Merryweather-Clarke AT, Pointon JJ et al (2000) Diagnosis and management of haemochromatosis since the discovery of the HFE gene: a European experience. Br J Haematol 108:31–39
Ros PR, Murphy BJ, Buck JL, Olmedilla G, Goodman Z (1990) Encapsulated hepatocellular carcinoma: radiologic findings and pathologic correlation. Gastrointest Radiol 15:233–237
Rückert JC, Konschake J, Kilian M. http://www.charite.de/ch/chir/chir/leist/lebzyst.htm
Schneider G, Siveke JT, Eckel F, Schmid RM (2005) Pancreatic cancer: basic and clinical aspects. Gastroenterology 128:1606–1625
Schreyer AG, Furst A, Agha A, Kikinis R, Scheibl K, Schölmerich J, Feuerbach S, Herfarth H, Seitz J (2004) Magnetic resonance imaging based colonography for diagnosis and assessment of diverticulosis and diverticulitis. Int J Colorectal Dis 19:474–480
Semelka RC, Sofka CM (1997) Hepatic hemangiomas. Magn Reson Imaging Clin N Am 5:241–253
Shaib Y, El-Serag HB (2004) The epidemiology of cholangiocarcinoma. Semin Liver Dis 24:115–125
Sica GT, Reed MF (2000) Case 27: intrapancreatic accessory spleen. Radiology 217:134–137
Soto JA, Barish MA, Alvarez O, Medina S (2000) Detection of choledocholithiasis with MR cholangiography: comparison of three-dimensional fast spin-echo and single and multi-section half-Fourier rapid acquisition with relaxation enhancement sequences. Radiology 215:737–745
Stocker JT, Ishak KG (1981) Focal nodular hyperplasia of the liver: a study of 21 pediatric cases. Cancer 48:336–345
Strobel D, Bernatik T (2006) Diagnostik bei fokalen Leberläsionen: Stellenwert der Kontrastmittelsonographie. Dtsch Arztebl 103:A789–A793
Sun XJ, Quan XY, Huang FH, Xu YK (2005) Quantitative evaluation of diffusion-weighted magnetic resonance imaging of focal hepatic lesions. World J Gastroenterol 11:6535–6537
Takagi H (1985) Diagnosis and management of cavernous hemangioma of the liver. Semin Surg Oncol 1:12–22
Tanaka M, Ikeda S, Yoshimoto S, Matsumoto S (1987) The long-term fate of the gallbladder after endoscopic sphincterotomy. Complete follow-up study of 122 patients. Am J Surg 154:505–509, III
Trastek VF, van Heerden JA, Sheedy PF 2nd, Adson MA (1983) Cavernous hemangiomas of the liver: resect or observe? Am J Surg 145:49–53
Velázquez RF, Rodríguez M, Navascués CA, Linares A, Pérez R, Sotorríos NG, Martínez I, Rodrigo L (2003) Prospective analysis of risk factors for hepatocellular carcinoma in patients with liver cirrhosis. Hepatology 37:520–527
Wahl HR (1951) Adrenal cysts. Am J Pathol 27:758
Warshaw AL, Compton CC, Lewandrowski K, Cardenosa G, Mueller PR (1990) Cystic tumors of the pancreas. New clinical, radiologic, and pathologic observations in 67 patients. Ann Surg 212:432–443
Wittenberg J, Stark DD, Forman BH, Hahn PF, Saini S, Weissleder R, Rummeny E, Ferrucci JT (1988) Differentiation of hepatic metastases from hepatic hemangiomas and cysts by using MR imaging. AJR Am J Roentgenol 151:79–84
Yun EJ (2003) Gallbladder carcinoma and chronic cholecystitis: differentiation with two-phase spiral CT. Abdom Imaging 29:102–108
Ziegler K, Sanft C, Zimmer T, Zeitz M, Felsenberg D, Stein H, Germer C, Deutschmann C, Riecken EO (1993) Comparison of computed tomography, endosonography, and intraoperative assessment in TN staging of gastric carcinoma. Gut 34:604–610
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Kühn, JP., Lühken, C. (2014). The Abdomen. In: Puls, R., Hosten, N. (eds) Whole-body MRI Screening. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-55201-4_8
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