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Properties of Hydrated Mineral Trioxide Aggregate

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Mineral Trioxide Aggregate in Dentistry

Abstract

Mineral trioxide aggregate (MTA) is composed of Portland cement and bismuth oxide as radiopacifying material. This chapter aimed at discussing the physicochemical and biological properties of MTA. When MTA is mixed with water, it hydrates to form a solid structure after 2–3 h. MTA has a compressive strength, which increases with time, and the adhesion and microhardness of the material are satisfactory and can be influenced by several factors. MTA exhibits slight expansion after setting. Most of the studies demonstrate that MTA is not soluble or presents low solubility when immersed in solution. MTA exhibits adequate sealing and has limited antimicrobial effect against some microorganisms. MTA might cause dental discoloration, which can compromise aesthetics. The amount of heavy metals released by MTA is a common concern with respect to the clinical application. In vitro studies have shown that MTA is biocompatible. Clinical research assessing the various uses of MTA compared to other standard materials has shown comparable clinical outcomes for all the materials tested.

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References

  1. Accorinte ML, Loguercio AD, Reis A, Bauer JR, Grande RH, Murata SS, Souza V, Holland R. Evaluation of two mineral trioxide aggregate compounds as pulp-capping agents in human teeth. Int Endod J. 2009;42(2):122–8.

    PubMed  Google Scholar 

  2. Aeinehchi M, Dadvand S, Fayazi S, Bayat-Movahed S. Randomized controlled trial of mineral trioxide aggregate and formocresol for pulpotomy in primary molar teeth. Int Endod J. 2007;40(4):261–7.

    PubMed  Google Scholar 

  3. Agamy HA, Bakry NS, Mounir MM, Avery DR. Comparison of mineral trioxide aggregate and formocresol as pulp-capping agents in pulpotomized primary teeth. Pediatr Dent. 2004;26(4):302–9.

    PubMed  Google Scholar 

  4. Airen P, Shigli A, Airen B. Comparative evaluation of formocresol and mineral trioxide aggregate in pulpotomized primary molars – 2 year follow up. J Clin Pediatr Dent. 2012;37(2):143–7.

    PubMed  Google Scholar 

  5. Akbari M, Rouhani A, Samiee S, Jafarzadeh H. Effect of dentin bonding agent on the prevention of tooth discoloration produced by mineral trioxide aggregate. Int J Dent. 2012;2012:563203.

    PubMed Central  PubMed  Google Scholar 

  6. Alanezi AZ, Zhu Q, Wang YH, Safavi KE, Jiang J. Effect of selected accelerants on setting time and biocompatibility of mineral trioxide aggregate (MTA). Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011;111(1):122–7.

    PubMed  Google Scholar 

  7. Al-Hezaimi K, Al-Shalan TA, Naghshbandi J, Oglesby S, Simon JH, Rotstein I. Antibacterial effect of two mineral trioxide aggregate (MTA) preparations against Enterococcus faecalis and Streptococcus sanguis in vitro. J Endod. 2006;32(11):1053–6.

    PubMed  Google Scholar 

  8. Al-Hezaimi K, Al-Shalan TA, Naghshbandi J, Simon JH, Rotstein I. MTA preparations from different origins may vary in their antimicrobial activity. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;107(5):e85–8.

    PubMed  Google Scholar 

  9. Al-Nazhan S, Al-Judai A. Evaluation of antifungal activity of mineral trioxide aggregate. J Endod. 2003;29(12):826–7.

    PubMed  Google Scholar 

  10. Andreasen JO, Munksgaard EC, Bakland LK. Comparison of fracture resistance in root canals of immature sheep teeth after filling with calcium hydroxide or MTA. Dent Traumatol. 2006;22:154–6.

    PubMed  Google Scholar 

  11. Ansari G, Ranjpour M. Mineral trioxide aggregate and formocresol pulpotomy of primary teeth: a 2-year follow-up. Int Endod J. 2010;43(5):413–8.

    PubMed  Google Scholar 

  12. Antunes Bortoluzzi E, Jua´rez Broon N, Antonio Hungaro Duarte M, de Oliveira Demarchi AC, Monteiro Bramante C. The use of a setting accelerator and its effect on pH and calcium ion release of mineral trioxide aggregate and white Portland cement. J Endod. 2006;32:1194–7.

    PubMed  Google Scholar 

  13. Arruda RA, Cunha RS, Miguita KB, Silveira CF, De Martin AS, Pinheiro SL, Rocha DG, Bueno CE. Sealing ability of mineral trioxide aggregate (MTA) combined with distilled water, chlorhexidine, and doxycycline. J Oral Sci. 2012;54(3):233–9.

    PubMed  Google Scholar 

  14. Asgary S, Eghbal MJ. Treatment outcomes of pulpotomy in permanent molars with irreversible pulpitis using biomaterials: a multi-center randomized controlled trial. Acta Odontol Scand. 2013;71(1):130–6.

    PubMed  Google Scholar 

  15. Balto HA. Attachment and morphological behavior of human periodontal ligament fibroblasts to mineral trioxide aggregate: a scanning electron microscope study. J Endod. 2004;30(1):25–9.

    PubMed  Google Scholar 

  16. Barrieshi-Nusair KM, Qudeimat MA. A prospective clinical study of mineral trioxide aggregate for partial pulpotomy in cariously exposed permanent teeth. J Endod. 2006;32(8):731–5.

    PubMed  Google Scholar 

  17. Bates CF, Carnes DL, del Rio CE. Longitudinal sealing ability of mineral trioxide aggregate as a root-end filling material. J Endod. 1996;22(11):575–8.

    PubMed  Google Scholar 

  18. Belı´o-Reyes IA, Bucio L, Cruz-Chavez E. Phase composition of ProRoot mineral trioxide aggregate by X-ray powder diffraction. J Endod. 2009;35:875–8.

    Google Scholar 

  19. Belobrov I, Parashos P. Treatment of tooth discoloration after the use of white mineral trioxide aggregate. J Endod. 2011;37(7):1017–20.

    PubMed  Google Scholar 

  20. Bernabé PF, Gomes-Filho JE, Bernabé DG, Nery MJ, Otoboni-Filho JA, Dezan-Jr E, Cintra LT. Sealing ability of MTA used as a root end filling material: effect of the sonic and ultrasonic condensation. Braz Dent J. 2013;24(2):107–10.

    PubMed  Google Scholar 

  21. Bidar M, Naderinasab M, Talati A, Ghazvini K, Asgari S, Hadizadeh B, Gharechahi M, Mashadi NA. The effects of different concentrations of chlorhexidine gluconate on the antimicrobial properties of mineral trioxide aggregate and calcium enrich mixture. Dent Res J (Isfahan). 2012;9(4):466–71.

    Google Scholar 

  22. Bortoluzzi EA, Araújo GS, Guerreiro Tanomaru JM, Tanomaru-Filho M. Marginal gingiva discoloration by gray MTA: a case report. J Endod. 2007;33(3):325–7.

    PubMed  Google Scholar 

  23. Bortoluzzi EA, Souza EM, Reis JM, Esberard RM, Tanomaru-Filho M. Fracture strength of bovine incisors after intra-radicular treatment with MTA in an experimental immature tooth model. Int Endod J. 2007;40(9):684–91.

    PubMed  Google Scholar 

  24. Bramante CM, Kato MM, Assis GF, Duarte MA, Bernardineli N, Moraes IG, Garcia RB, Ordinola-Zapata R, Bramante AS. Biocompatibility and setting time of CPM-MTA and white Portland cement clinker with or without calcium sulfate. J Appl Oral Sci. 2013;21(1):32–6.

    PubMed Central  PubMed  Google Scholar 

  25. Bueno CE, Zeferino EG, Manhães Jr LR, Rocha DG, Cunha RS, De Martin AS. Study of the bismuth oxide concentration required to provide Portland cement with adequate radiopacity for endodontic use. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;107(1):e65–9.

    PubMed  Google Scholar 

  26. Camargo CH, Fonseca MB, Carvalho AS, Camargo SE, Cardoso FG, Valera MC. Microhardness and sealing ability of materials used for root canal perforations. Gen Dent. 2012;60(6):e393–7.

    PubMed  Google Scholar 

  27. Camilleri J. Hydration mechanisms of mineral trioxide aggregate. Int Endod J. 2007;40:462–70.

    PubMed  Google Scholar 

  28. Camilleri J. Characterization of hydration products of mineral trioxide aggregate. Int Endod J. 2008;41:408–17.

    PubMed  Google Scholar 

  29. Camilleri J. Evaluation of the physical properties of an endodontic Portland cement incorporating alternative radiopacifiers used as root-end filling material. Int Endod J. 2010;43:231–40.

    PubMed  Google Scholar 

  30. Camilleri J. Evaluation of the effect of intrinsic material properties and ambient conditions on the dimensional stability of white mineral trioxide aggregate and Portland cement. J Endod. 2011;37(2):239–45.

    PubMed  Google Scholar 

  31. Camilleri J. The color stability of white mineral trioxide aggregate in contact with hypochlorite solution. J Endod. 2014;40(3):436–40.

    PubMed  Google Scholar 

  32. Camilleri J, Gandolfi MG. Evaluation of the radiopacity of calcium silicate cements containing different radiopacifiers. Int Endod J. 2010;43(1):21–30.

    PubMed  Google Scholar 

  33. Camilleri J, Kralj P, Veber M, Sinagra E. Characterization and analyses of acid-extractable and leached trace elements in dental cements. Int Endod J. 2012;45(8):737–43.

    PubMed  Google Scholar 

  34. Camilleri J, Montesin FE, Brady K, Sweeney R, Curtis RV, Ford TR. The constitution of mineral trioxide aggregate. Dent Mater. 2005;21:297–303.

    PubMed  Google Scholar 

  35. Camilleri J, Montesin FE, Di Silvio L, Pitt Ford TR. The chemical constitution and biocompatibility of accelerated Portland cement for endodontic use. Int Endod J. 2005;38(11):834–42.

    PubMed  Google Scholar 

  36. Camilleri J, Montesin FE, Papaioannou S, McDonald F, Pitt Ford TR. Biocompatibility of two commercial forms of mineral trioxide aggregate. Int Endod J. 2004;37(10):699–704.

    PubMed  Google Scholar 

  37. Camilleri J, Pitt Ford TR. Mineral trioxide aggregate: a review of the constituents and biological properties of the material. Int Endod J. 2006;39(10):747–54.

    PubMed  Google Scholar 

  38. Camilleri J, Sorrentino F, Damidot D. Investigation of the hydration and bioactivity of radiopacified tricalcium silicate cement, Biodentine and MTA Angelus. Dent Mater. 2013;29(5):580–93.

    PubMed  Google Scholar 

  39. Cardoso-Silva C, Barbería E, Maroto M, García-Godoy F. Clinical study of Mineral Trioxide Aggregate in primary molars. Comparison between Grey and White MTA-a long term follow-up (84 months). J Dent. 2011;39(2):187–93.

    PubMed  Google Scholar 

  40. Cauwels RG, Pieters IY, Martens LC, Verbeeck RM. Fracture resistance and reinforcement of immature roots with gutta percha, mineral trioxide aggregate and calcium phosphate bone cement: a standardized in vitro model. Dent Traumatol. 2010;26(2):137–42.

    PubMed  Google Scholar 

  41. Cavenago BC, Pereira TC, Duarte MA, Ordinola-Zapata R, Marciano MA, Bramante CM, Bernardineli N. Influence of powder-to-water ratio on radiopacity, setting time, pH, calcium ion release and a micro-CT volumetric solubility of white mineral trioxide aggregate. Int Endod J. 2014;47(2):120–6. doi:10.1111/iej.12120.

    PubMed  Google Scholar 

  42. Chang SW, Baek SH, Yang HC, Seo DG, Hong ST, Han SH, Lee Y, Gu Y, Kwon HB, Lee W, Bae KS, Kum KY. Heavy metal analysis of ortho MTA and ProRoot MTA. J Endod. 2011;37(12):1673–6.

    PubMed  Google Scholar 

  43. Chang SW, Shon WJ, Lee W, Kum KY, Baek SH, Bae KS. Analysis of heavy metal contents in gray and white MTA and 2 kinds of Portland cement: a preliminary study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109(4):642–6.

    PubMed  Google Scholar 

  44. Charland T, Hartwell GR, Hirschberg C, Patel R. An evaluation of setting time of mineral trioxide aggregate and EndoSequence root repair material in the presence of human blood and minimal essential media. J Endod. 2013;39(8):1071–2.

    PubMed  Google Scholar 

  45. Chng HK, Islam I, Yap AU, Tong YW, Koh ET. Properties of a new root-end filling material. J Endod. 2005;31:665–8.

    PubMed  Google Scholar 

  46. Chong BS. MTA or calcium hydroxide treatment for immature permanent teeth? Evid Based Dent. 2012;13(1):11.

    PubMed  Google Scholar 

  47. Chong BS, Pitt Ford TR, Hudson MB. A prospective clinical study of mineral trioxide aggregate and IRM when used as root-end filling materials in endodontic surgery. Int Endod J. 2003;36(8):520–6.

    PubMed  Google Scholar 

  48. Christiansen R, Kirkevang LL, Hørsted-Bindslev P, Wenzel A. Randomized clinical trial of root-end resection followed by root-end filling with mineral trioxide aggregate or smoothing of the orthograde gutta-percha root filling–1-year follow-up. Int Endod J. 2009;42(2):105–14.

    PubMed  Google Scholar 

  49. Coomaraswamy KS, Lumley PJ, Hofmann MP. Effect of bismuth oxide radioopacifier content on the material properties of an endodontic Portland cement-based (MTA-like) system. J Endod. 2007;33:295–8.

    PubMed  Google Scholar 

  50. Coutinho-Filho T, De-Deus G, Klein L, Manera G, Peixoto C, Gurgel-Filho ED. Radiopacity and histological assessment of Portland cement plus bismuth oxide. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;106(6):e69–77.

    PubMed  Google Scholar 

  51. da Silva GF, Guerreiro-Tanomaru JM, Sasso-Cerri E, Tanomaru-Filho M, Cerri PS. Histological and histomorphometrical evaluation of furcation perforations filled with MTA, CPM and ZOE. Int Endod J. 2011;44(2):100–10.

    PubMed  Google Scholar 

  52. Damle SG, Bhattal H, Loomba A. Apexification of anterior teeth: a comparative evaluation of mineral trioxide aggregate and calcium hydroxide paste. J Clin Pediatr Dent. 2012;36(3):263–8.

    PubMed  Google Scholar 

  53. Dammaschke T, Gerth HU, Züchner H, Schäfer E E. Chemical and physical surface and bulk material characterization of white ProRoot MTA and two Portland cements. Dent Mater. 2005;21:731–8.

    PubMed  Google Scholar 

  54. Danesh G, Dammaschke T, Gerth HU, Zandbiglari T, Schäfer E. A comparative study of selected properties of ProRoot mineral trioxide aggregate and two Portland cements. Int Endod J. 2006;39:213–9.

    PubMed  Google Scholar 

  55. Danesh F, Tootian Z, Jahanbani J, Rabiee M, Fazelipour S, Taghva O, Shabaninia S. Biocompatibility and mineralization activity of fresh or set white mineral trioxide aggregate, biomimetic carbonated apatite, and synthetic hydroxyapatite. J Endod. 2010;36(6):1036–41.

    PubMed  Google Scholar 

  56. De Bruyne MA, De Bruyne RJ, Rosiers L, De Moor RJ. Longitudinal study on microleakage of three root-end filling materials by the fluid transport method and by capillary flow porometry. Int Endod J. 2005;38(2):129–36.

    PubMed  Google Scholar 

  57. de Tenório de Franca TR, da Silva RJ, Sedycias de Queiroz M, Aguiar CM. Arsenic content in Portland cement: a literature review. Indian J Dent Res. 2010;21(4)):591–5.

    PubMed  Google Scholar 

  58. De-Deus G, Audi C, Murad C, Fidel S, Fidel R. Similar expression of through-and-through fluid movement along orthograde apical plugs of MTA Bio and white Portland cement. Int Endod J. 2008;41(12):1047–53.

    PubMed  Google Scholar 

  59. De-Deus G, de Souza MC, Sergio Fidel RA, Fidel SR, de Campos RC, Luna AS. Negligible expression of arsenic in some commercially available brands of Portland cement and mineral trioxide aggregate. J Endod. 2009;35(6):887–90.

    PubMed  Google Scholar 

  60. Doyle TL, Casas MJ, Kenny DJ, Judd PL. Mineral trioxide aggregate produces superior outcomes in vital primary molar pulpotomy. Pediatr Dent. 2010;32(1):41–7.

    PubMed  Google Scholar 

  61. Duarte MA, De Oliveira Demarchi AC, Yamashita JC, Kuga MC, De Campos Fraga S. Arsenic release provided by MTA and Portland cement. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;99(5):648–50.

    PubMed  Google Scholar 

  62. Eidelman E, Holan G, Fuks AB. Mineral trioxide aggregate vs. formocresol in pulpotomized primary molars: a preliminary report. Pediatr Dent. 2001;23(1):15–8.

    PubMed  Google Scholar 

  63. Eldeniz AU, Hadimli HH, Ataoglu H, Orstavik D. Antibacterial effect of selected root-end filling materials. J Endod. 2006;32(4):345–9.

    PubMed  Google Scholar 

  64. El-Meligy OA, Avery DR. Comparison of apexification with mineral trioxide aggregate and calcium hydroxide. Pediatr Dent. 2006;28(3):248–53.

    PubMed  Google Scholar 

  65. El-Meligy OA, Avery DR. Comparison of mineral trioxide aggregate and calcium hydroxide as pulpotomy agents in young permanent teeth (apexogenesis). Pediatr Dent. 2006;28(5):399–404.

    PubMed  Google Scholar 

  66. Erdem AP, Guven Y, Balli B, Ilhan B, Sepet E, Ulukapi I, Aktoren O. Success rates of mineral trioxide aggregate, ferric sulfate, and formocresol pulpotomies: a 24-month study. Pediatr Dent. 2011;33(2):165–70.

    PubMed  Google Scholar 

  67. Eskandarizadeh A, Shahpasandzadeh MH, Shahpasandzadeh M, Torabi M, Parirokh M. A comparative study on dental pulp response to calcium hydroxide, white and grey mineral trioxide aggregate as pulp capping agents. J Conserv Dent. 2011;14(4):351–5.

    PubMed Central  PubMed  Google Scholar 

  68. Estrela C, Bammann LL, Estrela CR, Silva RS, Pécora JD. Antimicrobial and chemical study of MTA, Portland cement, calcium hydroxide paste, Sealapex and Dycal. Braz Dent J. 2000;11(1):3–9.

    PubMed  Google Scholar 

  69. Farsi N, Alamoudi N, Balto K, Al Mushayt A. Clinical assessment of mineral trioxide aggregate (MTA) as direct pulp capping in young permanent teeth. J Clin Pediatr Dent. 2006;31(2):72–6.

    PubMed  Google Scholar 

  70. Farsi N, Alamoudi N, Balto K, Mushayt A. Success of mineral trioxide aggregate in pulpotomized primary molars. J Clin Pediatr Dent. 2005;29(4):307–11.

    PubMed  Google Scholar 

  71. Felman D, Parashos P. Coronal tooth discoloration and white mineral trioxide aggregate. J Endod. 2013;39(4):484–7.

    PubMed  Google Scholar 

  72. Fernández CC, Martínez SS, Jimeno FG, Lorente Rodríguez AI, Mercadé M. Clinical and radiographic outcomes of the use of four dressing materials in pulpotomized primary molars: a randomized clinical trial with 2-year follow-up. Int J Paediatr Dent. 2013;23(6):400–7.

    PubMed  Google Scholar 

  73. Ford TR, Torabinejad M, McKendry DJ, Hong CU, Kariyawasam SP. Use of mineral trioxide aggregate for repair of furcal perforations. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1995;79(6):756–63.

    PubMed  Google Scholar 

  74. Fridland M, Rosado R. Mineral trioxide aggregate (MTA) solubility and porosity with different water-to-powder ratios. J Endod. 2003;29(12):814–7.

    PubMed  Google Scholar 

  75. Fridland M, Rosado R. MTA solubility: a long term study. J Endod. 2005;31:376–9.

    PubMed  Google Scholar 

  76. Gancedo-Caravia L, Garcia-Barbero E. Influence of humidity and setting time on the push-out strength of mineral trioxide aggregate obturations. J Endod. 2006;32(9):894–6.

    PubMed  Google Scholar 

  77. Ghoddusi J, Sanaan A, Shahrami F. Clinical and radiographic evaluation of root perforation repair using MTA. N Y State Dent J. 2007;73(3):46–9.

    Google Scholar 

  78. Ghoddusi J, Shahrami F, Alizadeh M, Kianoush K, Forghani M. Clinical and radiographic evaluation of vital pulp therapy in open apex teeth with MTA and ZOE. N Y State Dent J. 2012;78(3):34–8.

    PubMed  Google Scholar 

  79. Giuliani V, Nieri M, Pace R, Pagavino G. Effects of pH on surface hardness and microstructure of mineral trioxide aggregate and Aureoseal: an in vitro study. J Endod. 2010;36(11):1883–6.

    PubMed  Google Scholar 

  80. Gonçalves JL, Viapiana R, Miranda CE, Borges AH, Cruz Filho AM. Evaluation of physico-chemical properties of Portland cements and MTA. Braz Oral Res. 2010;24(3):277–83. PubMed PMID: 20877963.

    PubMed  Google Scholar 

  81. Haglund R, He J, Jarvis J, Safavi KE, Spångberg LS, Zhu Q. Effects of root-end filling materials on fibroblasts and macrophages in vitro. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003;95(6):739–45.

    PubMed  Google Scholar 

  82. Hasan Zarrabi M, Javidi M, Naderinasab M, Gharechahi M. Comparative evaluation of antimicrobial activity of three cements: new endodontic cement (NEC), mineral trioxide aggregate (MTA) and Portland. J Oral Sci. 2009;51(3):437–42.

    PubMed  Google Scholar 

  83. Hatibovic´-Kofman S, Raimundo L, Zheng L, Chong L, Friedman M, Andreasen JO. Fracture resistance and histological findings of immature teeth treated with mineral trioxide aggregate. Dent Traumatol. 2008;24:272–6.

    PubMed  Google Scholar 

  84. Hilton TJ, Ferracane JL, Mancl L. Comparison of CaOH with MTA for direct pulp capping: a PBRN randomized clinical trial. J Dent Res. 2013;92(7 Suppl):16S–22.

    PubMed  Google Scholar 

  85. Hirschberg CS, Patel NS, Patel LM, Kadouri DE, Hartwell GR. Comparison of sealing ability of MTA and EndoSequence Bioceramic Root Repair Material: a bacterial leakage study. Quintessence Int. 2013;44(5):e157–62.

    PubMed  Google Scholar 

  86. Holan G, Eidelman E, Fuks AB. Long-term evaluation of pulpotomy in primary molars using mineral trioxide aggregate or formocresol. Pediatr Dent. 2005;27(2):129–36.

    PubMed  Google Scholar 

  87. Holland R, Bisco Ferreira L, de Souza V, Otoboni Filho JA, Murata SS, Dezan Jr E. Reaction of the lateral periodontium of dogs’ teeth to contaminated and noncontaminated perforations filled with mineral trioxide aggregate. J Endod. 2007;33(10):1192–7.

    PubMed  Google Scholar 

  88. Holland R, Filho JA, de Souza V, Nery MJ, Bernabé PF, Junior ED. Mineral trioxide aggregate repair of lateral root perforations. J Endod. 2001;27(4):281–4.

    PubMed  Google Scholar 

  89. Holt DM, Watts JD, Beeson TJ, Kirkpatrick TC, Rutledge RE. The anti-microbial effect against Enterococcus faecalis and the compressive strength of two types of mineral trioxide aggregate mixed with sterile water or 2 % chlorhexidine liquid. J Endod. 2007;33(7):844–7.

    PubMed  Google Scholar 

  90. International Standards Organization. ISO 9917-1. Dentistry-water-based cements. Part 1: powder/liquid acid–base cements. Geneva: International Standards Organization; 2007.

    Google Scholar 

  91. Islam I, Chng HK, Yap AU. X-ray diffraction analysis of mineral trioxide aggregate and Portland cement. Int Endod J. 2006;39:220–5.

    PubMed  Google Scholar 

  92. Islam I, Chng HK, Yap AU. Comparison of the physical and mechanical properties of MTA and Portland cement. J Endod. 2006;32:193–7.

    PubMed  Google Scholar 

  93. Iwamoto CE, Adachi E, Pameijer CH, Barnes D, Romberg EE, Jefferies S. Clinical and histological evaluation of white ProRoot MTA in direct pulp capping. Am J Dent. 2006;19(2):85–90.

    PubMed  Google Scholar 

  94. Kang JY, Lee BN, Son HJ, Koh JT, Kang SS, Son HH, Chang HS, Hwang IN, Hwang YC, Oh WM. Biocompatibility of mineral trioxide aggregate mixed with hydration accelerators. J Endod. 2013;39(4):497–500.

    PubMed  Google Scholar 

  95. Katsamakis S, Slot DE, Van der Sluis LW, Van der Weijden F. Histological responses of the periodontium to MTA: a systematic review. J Clin Periodontol. 2013;40(4):334–44.

    PubMed  Google Scholar 

  96. Kayahan MB, Nekoofar MH, Kazandağ M, Canpolat C, Malkondu O, Kaptan F, Dummer PM. Effect of acid-etching procedure on selected physical properties of mineral trioxide aggregate. Int Endod J. 2009;42(11):1004–14.

    PubMed  Google Scholar 

  97. Khalil WA, Eid NF. Biocompatibility of BioAggregate and mineral trioxide aggregate on the liver and kidney. Int Endod J. 2013;46(8):730–7.

    PubMed  Google Scholar 

  98. Koçak MM, Koçak S, Aktuna S, Görücü J, Yaman SD. Sealing ability of retrofilling materials following various root-end cavity preparation techniques. Lasers Med Sci. 2011;26(4):427–31.

    PubMed  Google Scholar 

  99. Krastl G, Allgayer N, Lenherr P, Filippi A, Taneja P, Weiger R. Tooth discoloration induced by endodontic materials: a literature review. Dent Traumatol. 2013;29(1):2–7.

    PubMed  Google Scholar 

  100. Kurita LM, Cavalcante RB, Gurgel-Filho ED, De-Deus GA, Ximenes AB, Da Silva EJ. Response of mice connective tissue to three different endodontic materials. Microsc Res Tech. 2013;76(3):311–5.

    PubMed  Google Scholar 

  101. Lee YL, Lee BS, Lin FH, Yun Lin A, Lan WH, Lin CP. Effects of physiological environments on the hydration behavior of mineral trioxide aggregate. Biomaterials. 2004;25(5):787–93.

    PubMed  Google Scholar 

  102. Lenherr P, Allgayer N, Weiger R, Filippi A, Attin T, Krastl G. Tooth discoloration induced by endodontic materials: a laboratory study. Int Endod J. 2012;45(10):942–9.

    PubMed  Google Scholar 

  103. Leye Benoist F, Gaye Ndiaye F, Kane AW, Benoist HM, Farge P. Evaluation of mineral trioxide aggregate (MTA) versus calcium hydroxide cement (Dycal(®)) in the formation of a dentine bridge: a randomised controlled trial. Int Dent J. 2012;62(1):33–9.

    PubMed  Google Scholar 

  104. Lindeboom JA, Frenken JW, Kroon FH, van den Akker HP. A comparative prospective randomized clinical study of MTA and IRM as root-end filling materials in single-rooted teeth in endodontic surgery. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;100(4):495–500.

    PubMed  Google Scholar 

  105. Liu H, Zhou Q, Qin M. Mineral trioxide aggregate versus calcium hydroxide for pulpotomy in primary molars. Chin J Dent Res. 2011;14(2):121–5.

    PubMed  Google Scholar 

  106. Lodiene G, Kleivmyr M, Bruzell E, Ørstavik D. Sealing ability of mineral trioxide aggregate, glass ionomer cement and composite resin when repairing large furcal perforations. Br Dent J. 2011;210(5):216–7.

    Google Scholar 

  107. Loxley EC, Liewehr FR, Buxton TB, McPherson 3rd JC. The effect of various intracanal oxidizing agents on the push-out strength of various perforation repair materials. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003;95(4):490–4.

    PubMed  Google Scholar 

  108. Malekafzali B, Shekarchi F, Asgary S. Treatment outcomes of pulpotomy in primary molars using two endodontic biomaterials. A 2-year randomised clinical trial. Eur J Paediatr Dent. 2011;12(3):189–93.

    PubMed  Google Scholar 

  109. Maltezos C, Glickman GN, Ezzo P, He J. Comparison of the sealing of Resilon, Pro Root MTA, and Super-EBA as root-end filling materials: a bacterial leakage study. J Endod. 2006;32(4):324–7.

    PubMed  Google Scholar 

  110. Maroto M, Barbería E, Planells P, García GF. Dentin bridge formation after mineral trioxide aggregate (MTA) pulpotomies in primary teeth. Am J Dent. 2005;18(3):151–4.

    PubMed  Google Scholar 

  111. Matsunaga T, Tsujimoto M, Kawashima T, Tsujimoto Y, Fujiwara M, Ookubo A, Hayashi Y. Analysis of arsenic in gray and white mineral trioxide aggregates by using atomic absorption spectrometry. J Endod. 2010;36(12):1988–90.

    PubMed  Google Scholar 

  112. Matt GD, Thorpe JR, Strother JM, McClanahan SB. Comparative study of white and gray mineral trioxide aggregate (MTA) simulating a one- or two-step apical barrier technique. J Endod. 2004;30:876–9.

    PubMed  Google Scholar 

  113. McNamara RP, Henry MA, Schindler WG, Hargreaves KM. Biocompatibility of accelerated mineral trioxide aggregate in a rat model. J Endod. 2010;36(11):1851–5.

    PubMed  Google Scholar 

  114. Mehrdad L, Malekafzali B, Shekarchi F, Safi Y, Asgary S. Histological and CBCT evaluation of a pulpotomised primary molar using calcium enriched mixture cement. Eur Arch Paediatr Dent. 2013;14(3):191–4.

    PubMed  Google Scholar 

  115. Miyagak DC, de Carvalho EM, Robazza CR, Chavasco JK, Levorato GL. In vitro evaluation of the antimicrobial activity of endodontic sealers. Braz Oral Res. 2006;20(4):303–6.

    PubMed  Google Scholar 

  116. Monteiro Bramante C, Demarchi AC, de Moraes IG, Bernadineli N, Garcia RB, Spångberg LS, Duarte MA. Presence of arsenic in different types of MTA and white and gray Portland cement. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;106(6):909–13.

    PubMed  Google Scholar 

  117. Moretti AB, Sakai VT, Oliveira TM, Fornetti AP, Santos CF, Machado MA, Abdo RC. The effectiveness of mineral trioxide aggregate, calcium hydroxide and formocresol for pulpotomies in primary teeth. Int Endod J. 2008;41(7):547–55.

    PubMed  Google Scholar 

  118. Naik S, Hegde AH. Mineral trioxide aggregate as a pulpotomy agent in primary molars: an in vivo study. J Indian Soc Pedod Prev Dent. 2005;23(1):13–6.

    PubMed  Google Scholar 

  119. Nair U, Ghattas S, Saber M, Natera M, Walker C, Pileggi R. A comparative evaluation of the sealing ability of 2 root-end filling materials: an in vitro leakage study using Enterococcus faecalis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011;112(2):e74–7.

    PubMed  Google Scholar 

  120. Namazikhah MS, Nekoofar MH, Sheykhrezae MS, Salariyeh S, Hayes SJ, Bryant ST, Mohammadi MM, Dummer PM. The effect of pH on surface hardness and microstructure of mineral trioxide aggregate. Int Endod J. 2008;41(2):108–16.

    PubMed  Google Scholar 

  121. Nekoofar MH, Adusei G, Sheykhrezae MS, Hayes SJ, Bryant ST, Dummer PM. The effect of condensation pressure on selected physical properties of mineral trioxide aggregate. Int Endod J. 2007;40(6):453–61.

    PubMed  Google Scholar 

  122. Nekoofar MH, Aseeley Z, Dummer PM. The effect of various mixing techniques on the surface microhardness of mineral trioxide aggregate. Int Endod J. 2010;43(4):312–20.

    PubMed  Google Scholar 

  123. Nekoofar MH, Oloomi K, Sheykhrezae MS, Tabor R, Stone DF, Dummer PM. An evaluation of the effect of blood and human serum on the surface microhardness and surface microstructure of mineral trioxide aggregate. Int Endod J. 2010;43(10):849–58.

    PubMed  Google Scholar 

  124. Noorollahian H. Comparison of mineral trioxide aggregate and formocresol as pulp medicaments for pulpotomies in primary molars. Br Dent J. 2008;204(11):E20.

    PubMed  Google Scholar 

  125. Nosrat A, Seifi A, Asgary S. Pulpotomy in caries-exposed immature permanent molars using calcium-enriched mixture cement or mineral trioxide aggregate: a randomized clinical trial. Int J Paediatr Dent. 2013;23(1):56–63.

    PubMed  Google Scholar 

  126. Odabaº ME, Cinar C, Akça G, Araz I, Ulusu T, Yücel H. Short-term antimicrobial properties of mineral trioxide aggregate with incorporated silver-zeolite. Dent Traumatol. 2011;27(3):189–94.

    Google Scholar 

  127. Odabaş ME, Alaçam A, Sillelioğlu H, Deveci C. Clinical and radiographic success rates of mineral trioxide aggregate and ferric sulphate pulpotomies performed by dental students. Eur J Paediatr Dent. 2012;13(2):118–22.

    PubMed  Google Scholar 

  128. Oliveira MG, Xavier CB, Demarco FF, Pinheiro AL, Costa AT, Pozza DH. Comparative chemical study of MTA and Portland cements. Braz Dent J. 2007;18:3–7.

    PubMed  Google Scholar 

  129. Oraie E, Ghassemi AR, Eliasifar G, Sadeghi M, Shahravan A. Apical sealing ability of MTA in different liquid to powder ratios and packing methods. Iran Endod J. 2012;7(1):5–9.

    PubMed Central  PubMed  Google Scholar 

  130. Osorio RM, Hefti A, Vertucci FJ, Shawley AL. Cytotoxicity of endodontic materials. J Endod. 1998;24(2):91–6.

    PubMed  Google Scholar 

  131. Ozdemir HO, elik B, Karabucak B, Cehreli ZC. Calcium ion diffusion from mineral trioxide aggregate through simulated root resorption defects. Dent Traumatol. 2008;24:70–3.

    PubMed  Google Scholar 

  132. Paranjpe A, Zhang H, Johnson JD. Effects of mineral trioxide aggregate on human dental pulp cells after pulp-capping procedures. J Endod. 2010;36(6):1042–7.

    PubMed  Google Scholar 

  133. Parirokh M, Torabinejad M. Mineral trioxide aggregate: a comprehensive literature review – part I: chemical, physical, and antibacterial properties. J Endod. 2010;36(1):16–27.

    PubMed  Google Scholar 

  134. Parirokh M, Torabinejad M. Mineral trioxide aggregate: a comprehensive literature review – part III: clinical applications, drawbacks, and mechanism of action. J Endod. 2010;36(3):400–13.

    PubMed  Google Scholar 

  135. Percinoto C, de Castro AM, Pinto LM. Clinical and radiographic evaluation of pulpotomies employing calcium hydroxide and trioxide mineral aggregate. Gen Dent. 2006;54(4):258–61.

    PubMed  Google Scholar 

  136. Petrou MA, Alhamoui FA, Welk A, Altarabulsi MB, Alkilzy M, H Splieth C. A randomized clinical trial on the use of medical Portland cement, MTA and calcium hydroxide in indirect pulp treatment. Clin Oral Investig. 2013. doi 10.1007/s00784-013-1107-z.

  137. Post LK, Lima FG, Xavier CB, Demarco FF, Gerhardt-Oliveira M. Sealing ability of MTA and amalgam in different root-end preparations and resection bevel angles: an in vitro evaluation using marginal dye leakage. Braz Dent J. 2010;21(5):416–9.

    PubMed  Google Scholar 

  138. Qudeimat MA, Barrieshi-Nusair KM, Owais AI. Calcium hydroxide vs mineral trioxide aggregates for partial pulpotomy of permanent molars with deep caries. Eur Arch Paediatr Dent. 2007;8(2):99–104.

    PubMed  Google Scholar 

  139. Reyes-Carmona JF, Felippe MS, Felippe WT. The biomineralization ability of mineral trioxide aggregate and Portland cement on dentin enhances the push-out strength. J Endod. 2010;36(2):286–91.

    PubMed  Google Scholar 

  140. Ribeiro DA, Duarte MA, Matsumoto MA, Marques ME, Salvadori DM. Biocompatibility in vitro tests of mineral trioxide aggregate and regular and white Portland cements. J Endod. 2005;31(8):605–7.

    PubMed  Google Scholar 

  141. Ribeiro CS, Kuteken FA, Hirata Júnior R, Scelza MF. Comparative evaluation of antimicrobial action of MTA, calcium hydroxide and Portland cement. J Appl Oral Sci. 2006;14(5):330–3.

    PubMed  Google Scholar 

  142. Ribeiro DA, Matsumoto MA, Duarte MA, Marques ME, Salvadori DM. Ex vivo biocompatibility tests of regular and white forms of mineral trioxide aggregate. Int Endod J. 2006;39(1):26–30.

    PubMed  Google Scholar 

  143. Ribeiro CS, Scelza MF, Hirata Júnior R, Buarque de Oliveira LM. The antimicrobial activity of gray-colored mineral trioxide aggregate (GMTA) and white-colored MTA (WMTA) under aerobic and anaerobic conditions. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109(6):e109–12.

    PubMed  Google Scholar 

  144. Roberts HW, Toth JM, Berzins DW, Charlton DG. Mineral trioxide aggregate material use in endodontic treatment: a review of the literature. Dent Mater. 2008;24(2):149–64.

    PubMed  Google Scholar 

  145. Saatchi M, Hosseini HS, Farhad AR, Narimany T. The effect of various concentrations of iodine potassium iodide on the antimicrobial properties of mineral trioxide aggregate – a pilot study. Dent Traumatol. 2012;28(6):474–7.

    PubMed  Google Scholar 

  146. Saghiri MA, Asgar K, Lotfi M, Garcia-Godoy F. Nanomodification of mineral trioxide aggregate for enhanced physiochemical properties. Int Endod J. 2012;45(11):979–88.

    PubMed  Google Scholar 

  147. Saghiri MA, Asgar K, Lotfi M, Karamifar K, Neelakantan P, Ricci JL. Application of mercury intrusion porosimetry for studying the porosity of mineral trioxide aggregate at two different pH. Acta Odontol Scand. 2012;70(1):78–82.

    PubMed  Google Scholar 

  148. Saghiri MA, Asgar K, Lotfi M, Nazari A, Karamifar K, Neelakantan P, Gutmann JL. Effect of storage temperature on sealing ability and solubility of white mineral trioxide aggregate. Acta Odontol Scand. 2012;70(6):536–40.

    PubMed  Google Scholar 

  149. Saghiri MA, Garcia-Godoy F, Gutmann JL, Lotfi M, Asatourian A, Ahmadi H. Push-out bond strength of a nano-modified mineral trioxide aggregate. Dent Traumatol. 2013;29(4):323–7.

    PubMed  Google Scholar 

  150. Saghiri MA, Garcia-Godoy F, Lotfi M, Ahmadi H, Asatourian A. Effects of diode laser and MTAD on the push-out bond strength of mineral trioxide aggregate-dentin interface. Photomed Laser Surg. 2012;30(10):587–91.

    PubMed  Google Scholar 

  151. Saghiri MA, Lotfi M, Joupari MD, Aeinehchi M, Saghiri AM. Effects of storage temperature on surface hardness, microstructure, and phase formation of white mineral trioxide aggregate. J Endod. 2010;36(8):1414–8.

    PubMed  Google Scholar 

  152. Saghiri MA, Shokouhinejad N, Lotfi M, Aminsobhani M, Saghiri AM. Push-out bond strength of mineral trioxide aggregate in the presence of alkaline pH. J Endod. 2010;36(11):1856–9.

    PubMed  Google Scholar 

  153. Saidon J, He J, Zhu Q, Safavi K, Spångberg LS. Cell and tissue reactions to mineral trioxide aggregate and Portland cement. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003;95(4):483–9.

    PubMed  Google Scholar 

  154. Sakai VT, Moretti AB, Oliveira TM, Fornetti AP, Santos CF, Machado MA, Abdo RC. Pulpotomy of human primary molars with MTA and Portland cement: a randomized controlled trial. Br Dent J. 2009;207(3):E5; discussion 128–9.

    PubMed  Google Scholar 

  155. Saliba E, Abbassi-Ghadi S, Vowles R, Camilleri J, Hooper S, Camilleri J. Evaluation of the strength and radiopacity of Portland cement with varying additions of bismuth oxide. Int Endod J. 2009;42(4):322–8.

    PubMed  Google Scholar 

  156. Saunders WP. A prospective clinical study of periradicular surgery using mineral trioxide aggregate as a root-end filling. J Endod. 2008;34(6):660–5.

    PubMed  Google Scholar 

  157. Schembri M, Peplow G, Camilleri J. Analyses of heavy metals in mineral trioxide aggregate and Portland cement. J Endod. 2010;36(7):1210–5.

    PubMed  Google Scholar 

  158. Shah N, Logani A, Bhaskar U, Aggarwal V. Efficacy of revascularization to induce apexification/apexogensis in infected, nonvital, immature teeth: a pilot clinical study. J Endod. 2008;34(8):919–25; discussion 1157.

    PubMed  Google Scholar 

  159. Shahi S, Rahimi S, Lotfi M, Yavari H, Gaderian A. A comparative study of the biocompatibility of three root-end filling materials in rat connective tissue. J Endod. 2006;32(8):776–80.

    PubMed  Google Scholar 

  160. Shahi S, Yavari HR, Rahimi S, Eskandarinezhad M, Shakouei S, Unchi M. Comparison of the sealing ability of mineral trioxide aggregate and Portland cement used as root-end filling materials. J Oral Sci. 2011;53(4):517–22.

    PubMed  Google Scholar 

  161. Shie MY, Huang TH, Kao CT, Huang CH, Ding SJ. The effect of a physiologic solution pH on properties of white mineral trioxide aggregate. J Endod. 2009;35:98–101.

    PubMed  Google Scholar 

  162. Shokouhinejad N, Nekoofar MH, Iravani A, Kharrazifard MJ, Dummer PM. Effect of acidic environment on the push-out bond strength of mineral trioxide aggregate. J Endod. 2010;36(5):871–4.

    PubMed  Google Scholar 

  163. Simon S, Rilliard F, Berdal A, Machtou P. The use of mineral trioxide aggregate in one-visit apexification treatment: a prospective study. Int Endod J. 2007;40(3):186–97.

    PubMed  Google Scholar 

  164. Sluyk SR, Moon PC, Hartwell GR. Evaluation of setting properties and retention characteristics of mineral trioxide aggregate when used as a furcation perforation repair material. J Endod. 1998;24:768–71.

    PubMed  Google Scholar 

  165. Song M, Kim E. A prospective randomized controlled study of mineral trioxide aggregate and super ethoxy-benzoic acid as root-end filling materials in endodontic microsurgery. J Endod. 2012;38(7):875–9.

    PubMed  Google Scholar 

  166. Sonmez D, Sari S, Cetinbaş T. A comparison of four pulpotomy techniques in primary molars: a long-term follow-up. J Endod. 2008;34(8):950–5.

    PubMed  Google Scholar 

  167. Srinivasan D, Jayanthi M. Comparative evaluation of formocresol and mineral trioxide aggregate as pulpotomy agents in deciduous teeth. Indian J Dent Res. 2011;22(3):385–90.

    PubMed  Google Scholar 

  168. Storm B, Eichmiller FC, Tordik PA, Goodell GG. Setting expansion of gray and white mineral trioxide aggregate and Portland cement. J Endod. 2008;34:80–2.

    PubMed  Google Scholar 

  169. Stowe TJ, Sedgley CM, Stowe B, Fenno JC. The effects of chlorhexidine gluconate (0.12 %) on the antimicrobial properties of tooth-colored ProRoot mineral trioxide aggregate. J Endod. 2004;30(6):429–31.

    PubMed  Google Scholar 

  170. Subramaniam P, Konde S, Mathew S, Sugnani S. Mineral trioxide aggregate as pulp capping agent for primary teeth pulpotomy: 2 year follow up study. J Clin Pediatr Dent. 2009;33(4):311–4.

    PubMed  Google Scholar 

  171. Sushynski JM, Zealand CM, Botero TM, Boynton JR, Majewski RF, Shelburne CE, Hu JC. Comparison of gray mineral trioxide aggregate and diluted formocresol in pulpotomized primary molars: a 6- to 24-month observation. Pediatr Dent. 2012;34(5):120–8.

    PubMed  Google Scholar 

  172. Tanomaru-Filho M, Faleiros FB, Silva GF, Bosso R, Guerreiro-Tanomaru JM. Sealing ability of retrograde obturation materials containing calcium hydroxide or MTA. Acta Odontol Latinoam. 2011;24(1):110–4.

    PubMed  Google Scholar 

  173. Tanomaru-Filho M, Luis MR, Leonardo MR, Tanomaru JM, Silva LA. Evaluation of periapical repair following retrograde filling with different root-end filling materials in dog teeth with periapical lesions. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;102(1):127–32.

    PubMed  Google Scholar 

  174. Tanomaru-Filho M, Tanomaru JM, Barros DB, Watanabe E, Ito IY. In vitro antimicrobial activity of endodontic sealers, MTA-based cements and Portland cement. J Oral Sci. 2007;49(1):41–5.

    PubMed  Google Scholar 

  175. Torabinejad M, Higa RK, McKendry DJ, Pitt Ford TR. Dye leakage of four root end filling materials: effects of blood contamination. J Endod. 1994;20(4):159–63.

    PubMed  Google Scholar 

  176. Torabinejad M, Hong CU, Lee SJ, Monsef M, Pitt Ford TR. Investigation of mineral trioxide aggregate for root-end filling in dogs. J Endod. 1995;21(12):603–8.

    PubMed  Google Scholar 

  177. Torabinejad M, Hong CU, McDonald F, Pitt Ford TR. Physical and chemical properties of a new root-end filling material. J Endod. 1995;21:349–53.

    PubMed  Google Scholar 

  178. Torabinejad M, Hong CU, Pitt Ford TR, Kaiyawasam SP. Tissue reaction to implanted super-EBA and mineral trioxide aggregate in the mandible of guinea pigs: a preliminary report. J Endod. 1995;21(11):569–71.

    PubMed  Google Scholar 

  179. Torabinejad M, Hong CU, Pitt Ford TR, Kettering JD. Antibacterial effects of some root end filling materials. J Endod. 1995;21(8):403–6.

    PubMed  Google Scholar 

  180. Torabinejad M, Parirokh M. Mineral trioxide aggregate: a comprehensive literature review – part II: leakage and biocompatibility investigations. J Endod. 2010;36(2):190–202.

    PubMed  Google Scholar 

  181. Torabinejad M, Pitt Ford TR, McKendry DJ, Abedi HR, Miller DA, Kariyawasam SP. Histologic assessment of mineral trioxide aggregate as a root-end filling in monkeys. J Endod. 1997;23(4):225–8.

    PubMed  Google Scholar 

  182. Torabinejad M, Rastegar AF, Kettering JD, Pitt Ford TR. Bacterial leakage of mineral trioxide aggregate as a root-end filling material. J Endod. 1995;21(3):109–12.

    PubMed  Google Scholar 

  183. Torabinejad M, Smith PW, Kettering JD, Pitt Ford TR. Comparative investigation of marginal adaptation of mineral trioxide aggregate and other commonly used root-end filling materials. J Endod. 1995;21(6):295–9.

    PubMed  Google Scholar 

  184. Torabinejad M, Watson TF, Pitt Ford TR. Sealing ability of a mineral trioxide aggregate when used as a root end filling material. J Endod. 1993;19:591–5.

    PubMed  Google Scholar 

  185. Torabinejad M, White DJ, inventors; Loma Linda University, assignee. Tooth filling material and use. United States Patent Number 5,769,638. 16 May 1995.

    Google Scholar 

  186. Tuna D, Olmez A. Clinical long-term evaluation of MTA as a direct pulp capping material in primary teeth. Int Endod J. 2008;41(4):273–8.

    PubMed  Google Scholar 

  187. Uyanik MO, Nagas E, Sahin C, Dagli F, Cehreli ZC. Effects of different irrigation regimens on the sealing properties of repaired furcal perforations. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;107(3):e91–5.

    PubMed  Google Scholar 

  188. Vallés M, Mercadé M, Duran-Sindreu F, Bourdelande JL, Roig M. Color stability of white mineral trioxide aggregate. Clin Oral Investig. 2013;17(4):1155–9.

    PubMed  Google Scholar 

  189. Vallés M, Mercadé M, Duran-Sindreu F, Bourdelande JL, Roig M. Influence of light and oxygen on the color stability of five calcium silicate-based materials. J Endod. 2013;39(4):525–8.

    PubMed  Google Scholar 

  190. Vivan RR, Ordinola-Zapata R, Bramante CM, Bernardineli N, Garcia RB, Hungaro Duarte MA, de Moraes IG. Evaluation of the radiopacity of some commercial and experimental root-end filling materials. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;108(6):e35–8.

    PubMed  Google Scholar 

  191. von Arx T, Hänni S, Jensen SS. Clinical results with two different methods of root-end preparation and filling in apical surgery: mineral trioxide aggregate and adhesive resin composite. J Endod. 2010;36(7):1122–9.

    Google Scholar 

  192. Wälivaara DÅ, Abrahamsson P, Isaksson S, Salata LA, Sennerby L, Dahlin C. Periapical tissue response after use of intermediate restorative material, gutta-percha, reinforced zinc oxide cement, and mineral trioxide aggregate as retrograde root-end filling materials: a histologic study in dogs. J Oral Maxillofac Surg. 2012;70(9):2041–7.

    PubMed  Google Scholar 

  193. Yasuda Y, Kamaguchi A, Saito T. In vitro evaluation of the antimicrobial activity of a new resin-based endodontic sealer against endodontic pathogens. J Oral Sci. 2008;50(3):309–13.

    PubMed  Google Scholar 

  194. Yildirim T, Er K, Taşdemir T, Tahan E, Buruk K, Serper A. Effect of smear layer and root-end cavity thickness on apical sealing ability of MTA as a root-end filling material: a bacterial leakage study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109(1):e67–72.

    PubMed  Google Scholar 

  195. Yildirim T, Oruçoğlu H, Cobankara FK. Long-term evaluation of the influence of smear layer on the apical sealing ability of MTA. J Endod. 2008;34(12):1537–40.

    PubMed  Google Scholar 

  196. Zealand CM, Briskie DM, Botero TM, Boynton JR, Hu JC. Comparing gray mineral trioxide aggregate and diluted formocresol in pulpotomized human primary molars. Pediatr Dent. 2010;32(5):393–9.

    PubMed  Google Scholar 

  197. Zhu Q, Haglund R, Safavi KE, Spangberg LS. Adhesion of human osteoblasts on root-end filling materials. J Endod. 2000;26(7):404–6.

    PubMed  Google Scholar 

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  1. Department of Restorative Dentistry, Araraquara School of Dentistry, UNESP – São Paulo State University, Rua Humaitá 1680, Araraquara, SP, 14801-903, Brazil

    Mario Tanomaru-Filho PhD & Juliane Maria Guerreiro-Tanomaru PhD

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    Josette Camilleri

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Tanomaru-Filho, M., Guerreiro-Tanomaru, J.M. (2014). Properties of Hydrated Mineral Trioxide Aggregate. In: Camilleri, J. (eds) Mineral Trioxide Aggregate in Dentistry. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-55157-4_3

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