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Event-Related Desynchronization by Hand Motor Imagery Is Associated with Corticospinal Excitability: Physiological Evidence for BCI Based Neurorehabilitation

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Brain-Computer Interface Research

Part of the book series: Biosystems & Biorobotics ((BIOSYSROB,volume 6))

Abstract

The purpose of this study was to assess the association between the magnitude of event-related desynchronization (ERD) of electroencephalogram, which is believed to represent increased activation of the sensorimotor cortex, and the excitability of primary motor cortex (M1) and spinal motoneurons. M1 excitability was tested by motor evoked potentials (MEPs), short-interval intracortical inhibition (SICI) and intracortical facilitation (ICF) using transcranial magnetic stimulation, and spinal motoneuronal excitability was tested by F-waves using peripheral nerve stimulation. Results showed that MEP amplitude was significantly increased during motor imagery and large ERD during motor imagery was associated with significantly reduced SICI and increased F-wave persistence, but no significant changes in ICF and the response average of F-wave amplitudes. Our findings suggest that ERD magnitude during motor imagery reflects the instantaneous excitability of both M1 and spinal motoneurons.

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Authors and Affiliations

  1. Graduate School of Science and Technology, Keio University, Kanagawa, Japan

    Mitsuaki Takemi

  2. Department of Rehabilitation Medicine, School of Medicine, Tokai University, Kanagawa, Japan

    Yoshihisa Masakado

  3. Department of Rehabilitation Medicine, School of Medicine, Keio University, Tokyo, Japan

    Meigen Liu & Junichi Ushiba

  4. Faculty of Science and Technology, Keio University, Kanagawa, Japan

    Junichi Ushiba

Authors
  1. Mitsuaki Takemi
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  2. Yoshihisa Masakado
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  3. Meigen Liu
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  4. Junichi Ushiba
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Corresponding author

Correspondence to Mitsuaki Takemi .

Editor information

Editors and Affiliations

  1. g.tec medical engineering GmbH/ Guger Technologies OG, Schiedlberg, Austria

    Christoph Guger

  2. Cognitive Science Dept, UC San Diego, La Jolla, USA

    Brendan Allison

  3. Department of Neurosurgery School of Medicine, Washington University in St. Louis, St. Louis, Missouri, USA

    E.C. Leuthardt

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Takemi, M., Masakado, Y., Liu, M., Ushiba, J. (2014). Event-Related Desynchronization by Hand Motor Imagery Is Associated with Corticospinal Excitability: Physiological Evidence for BCI Based Neurorehabilitation. In: Guger, C., Allison, B., Leuthardt, E. (eds) Brain-Computer Interface Research. Biosystems & Biorobotics, vol 6. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-54707-2_9

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  • DOI: https://doi.org/10.1007/978-3-642-54707-2_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-54706-5

  • Online ISBN: 978-3-642-54707-2

  • eBook Packages: EngineeringEngineering (R0)

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