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Schwere blasenbildende Hautreaktionen

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Verbrennungschirurgie

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Zusammenfassung

Schwere blasenbildenden Hautreaktionen sind seltene, aber lebensbedrohliche Erkrankungen, die Menschen aller Altersgruppen und Herkunft betreffen können. Sie sind nicht vorhersehbar und entwickeln sich häufig sehr rasch von einem fleckigen Ausschlag bis hin zu einem Bild, das an eine großflächige Verbrühung der Haut erinnert, wobei die Schleimhäute fast immer mit betroffen sind. Hierzu gehören vor allem das Stevens-Johnson-Syndrom (SJS) und die toxisch epidermale Nekrolyse (TEN), die als eine Krankheitsentität mit verschiedenem Schweregrad gelten. Sie müssen von anderen blasenbildenden Hauterkrankungen abgegrenzt werden, da eine klare Diagnose die Vorrausetzung für eine adäquate Behandlung ist. Als auslösende Faktoren kommen in erster Linie Arzneimittel in Betracht, weniger häufig Infekte, aber auch »idiopathische« Fälle werden beobachtet. Die mögliche Ursache der Reaktion zu finden und zu beseitigen, ist wichtig für die Prognose des Patienten, ebenso wie alle anderen therapeutischen Maßnahmen.

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Author information

Authors and Affiliations

  1. Klinik für Dermatologie und Venerologie, Universitätsklinikum Freiburg, Hauptstraße 7, D-79104, Freiburg

    Prof. Dr. med. Maja Mockenhaupt

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  1. Prof. Dr. med. Maja Mockenhaupt
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Editors and Affiliations

  1. BG-Universitätsklinikum Bergmannsheil Bochum, Bochum, Deutschland

    Marcus Lehnhardt

  2. Unfallkrankenhaus Berlin, Berlin, Deutschland

    Bernd Hartmann

  3. Klinikum Nürnberg, Nürnberg, Deutschland

    Bert Reichert

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Mockenhaupt, M. (2016). Schwere blasenbildende Hautreaktionen. In: Lehnhardt, M., Hartmann, B., Reichert, B. (eds) Verbrennungschirurgie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-54444-6_36

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  • DOI: https://doi.org/10.1007/978-3-642-54444-6_36

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-54443-9

  • Online ISBN: 978-3-642-54444-6

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