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Corneal Inflammation Following Excimer Laser Surgery

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Immune Modulation and Anti-Inflammatory Therapy in Ocular Disorders

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Abstract

Millions of surface ablation excimer laser surgeries are performed worldwide. The normal cornea, when photoablated, reacts in a way specific to this process. The fundamentals of this biological reactivity are based on the normal structure of the photoablated cornea and on the energy delivered by the laser.

Adequate management of postoperative inflammation is essential after photorefractive procedures. Successful modulation of the biochemical inflammatory process and cellular wound healing response seems to be important after surface procedures to achieve an excellent visual outcome. Finally, early detection and a suitable therapeutic approach can prevent undesirable sequelae of specific inflammatory conditions such as DLK, CTK, or TLSS.

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Authors and Affiliations

  1. Anterior Segment and Refractive Surgery, VISSUM Alicante (Spain), Cabañal s/n. Pinar de Vistahermosa, Alicante, Alicante, 03016, Spain

    Jaime Javaloy MD, PhD

  2. Department of Ophthalmology, Miguel Hernández University of Elche, Alicante, Spain

    Jaime Javaloy MD, PhD

  3. Department of Ophthalmology, Miguel Hernandez University, Vissum-Instituto Oftalmologico, Alicante, Spain

    Jorge L. Alió MD, PhD

  4. Vissum-Instituto Oftalmologico de Alicante, Vissum Corporation, Spain, Avda de Denia s/n, Edificio Vissum, Alicante, 03016, Spain

    Jorge L. Alió MD, PhD

  5. Cornea, Cataract and Refractive Surgery, Vissum Corporacion, Calle Cabañal s/n, Alicante, 03016, Spain

    Alfredo Vega Estrada MD

Authors
  1. Jaime Javaloy MD, PhD
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  2. Jorge L. Alió MD, PhD
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  3. Alfredo Vega Estrada MD
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Corresponding author

Correspondence to Jorge L. Alió MD, PhD .

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Editors and Affiliations

  1. Department of Ophthalmology, Charité Campus Virchow-Klinikum, Berlin, Germany

    Uwe Pleyer

  2. Division of Ophthalmology, Miguel Hernandez University, Vissum-Instituto Oftalmologico de Alicante, Alicante, Spain

    Jorge L. Alió

  3. Centre of Ocular Inflammation and Infection OCUVAC, Medical University of Vienna Laura Bassi Centre of Expertise, Vienna, Austria

    Talin Barisani-Asenbauer

  4. Department of Ophthalmology, Pitié-Salpêtrière’s University Hospital, Paris, France

    Phuc Le Hoang

  5. Doheny Eye Institute, University of Southern California Keck School of Medicine, Los Angeles, California, USA

    Narsing A. Rao

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Javaloy, J., Alió, J.L., Estrada, A.V. (2014). Corneal Inflammation Following Excimer Laser Surgery. In: Pleyer, U., Alió, J., Barisani-Asenbauer, T., Le Hoang, P., Rao, N. (eds) Immune Modulation and Anti-Inflammatory Therapy in Ocular Disorders. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-54350-0_5

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