Skip to main content
SpringerLink
Log in

Classification of Uveal Tumors

  • Chapter
  • First Online:
Clinical Ophthalmic Oncology

  • 822 Accesses

Abstract

Tumors of the same class should share a unique combination of features, which distinguishes them from all other classes [1, 2]. Classification, therefore, is the process of defining different tumor classes and correlating these with each other in a hierarchical manner. Classification must be distinguished from “discrimination,” which involves “grading” of morphological features and “staging” of clinical tumor behavior.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Berman JJ. Tumor classification: molecular analysis meets Aristotle. BMC Cancer. 2004;4:10.

    Article  PubMed Central  PubMed  Google Scholar 

  2. Berman J. Modern classification of neoplasms: reconciling differences between morphologic and molecular approaches. BMC Cancer. 2005;5:100.

    Article  PubMed Central  PubMed  Google Scholar 

  3. Campbell RJ. Histological typing of tumours of the eye and its adnexa. Berlin: Springer; 1998.

    Book  Google Scholar 

  4. Coupland SE, Lake SL, Zeschnigk M, Damato BE. Molecular pathology of uveal melanoma. Eye (Lond). 2013;27(2):230–42.

    Article  CAS  Google Scholar 

  5. Damato B, Dopierala JA, Coupland SE. Genotypic profiling of 452 choroidal melanomas with multiplex ligation-dependent probe amplification. Clin Cancer Res. 2010;16(24):6083–92.

    Article  CAS  PubMed  Google Scholar 

  6. Onken MD, Worley LA, Char DH, Augsburger JJ, Correa ZM, Nudleman E, et al. Collaborative Ocular Oncology Group report number 1: prospective validation of a multi-gene prognostic assay in uveal melanoma. Ophthalmology. 2012;119:1596–603.

    Article  PubMed Central  PubMed  Google Scholar 

  7. Callejo SA, Dopierala J, Coupland SE, Damato B. Sudden growth of a choroidal melanoma and multiplex ligation-dependent probe amplification findings suggesting late transformation to monosomy 3 type. Arch Ophthalmol. 2011;129(7):958–60.

    Article  PubMed  Google Scholar 

  8. Onken MD, Worley LA, Ehlers JP, Harbour JW. Gene expression profiling in uveal melanoma reveals two molecular classes and predicts metastatic death. Cancer Res. 2004;64(20):7205–9.

    Article  CAS  PubMed  Google Scholar 

  9. Gospodarowicz MK, Miller D, Groome PA, Greene FL, Logan PA, Sobin LH. The process for continuous improvement of the TNM classification. Cancer. 2004;100(1):1–5.

    PubMed  Google Scholar 

  10. American Joint Committee on Cancer. AJCC cancer staging manual. 7th ed. New York: Springer; 2010.

    Book  Google Scholar 

  11. Kujala E, Damato B, Coupland SE, Desjardins L, Bechrakis NE, Grange JD, Kivelä T. Staging of ciliary body and choroidal melanomas based on anatomic extent. J Clin Oncol. 2013;31(22):2825–31.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Ocular Oncology Service, Departments of Ophthalmology and Radiation Oncology, University of California San Francisco, 10 Koret Way, San Francisco, CA, 94143, USA

    Bertil Damato MD, PhD

  2. Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, 6th Floor Duncan Building, Daulby Street, Liverpool, L69 3GA, UK

    Sarah E. Coupland MBBS, PhD

Authors
  1. Bertil Damato MD, PhD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Sarah E. Coupland MBBS, PhD
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Bertil Damato MD, PhD .

Editor information

Editors and Affiliations

  1. Ocular Oncology Service, Departments of Ophthalmology and Radiation Oncology, University of California, San Francisco, San Francisco, California, USA

    Bertil Damato

  2. Dept. of Ophthalmic Oncology, Cole Eye Institute Cleveland Clinic Foundation, Cleveland, Ohio, USA

    Arun D. Singh

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Damato, B., Coupland, S.E. (2014). Classification of Uveal Tumors. In: Damato, B., Singh, A. (eds) Clinical Ophthalmic Oncology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-54255-8_2

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-54255-8_2

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-54254-1

  • Online ISBN: 978-3-642-54255-8

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation