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Mammalian Transient Receptor Potential (TRP) Cation Channels pp 1–12Cite as

TRPs: Truly Remarkable Proteins

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Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 222))

Abstract

The family of transient receptor potential cation channels has received in the last 10 years a tremendous interest because members of this family are involved in a plethora of cell functions and have been identified as causal for many hereditary and acquired diseases. We shortly introduce these channels, summarize nomenclature and chromosomal location of the 28 mammalian Trp genes, and list the available Trp-deficient mouse lines.

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Authors and Affiliations

  1. Institut für Experimentelle und Klinische Pharmakologie und Toxikologie, Universität des Saarlandes, Gebäude 46, 66421, Homburg, Germany

    Veit Flockerzi

  2. Laboratory Ion Channel Research, Department Cell Mol Medicine, KU Leuven, Campus Gasthuisberg, O&N 1, Herestraat 49-Bus 802, 3000, Leuven, Belgium

    Bernd Nilius

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  1. Veit Flockerzi
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  2. Bernd Nilius
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Correspondence to Veit Flockerzi or Bernd Nilius .

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Editors and Affiliations

  1. Laboratory Ion Channel Research Campus Gasthuisberg, KU Leuven Department Cell Mol Medicin, Leuven, Belgium

    Bernd Nilius

  2. Institut für Experimentelle u. Klinische, Pharmakologie und Toxikologie, Universität des Saarlandes, Homburg, Saarland, Germany

    Veit Flockerzi

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Flockerzi, V., Nilius, B. (2014). TRPs: Truly Remarkable Proteins. In: Nilius, B., Flockerzi, V. (eds) Mammalian Transient Receptor Potential (TRP) Cation Channels. Handbook of Experimental Pharmacology, vol 222. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-54215-2_1

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