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Gray Matter Diseases of the Spinal Cord

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Diseases of the Spinal Cord

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Abstract

Gray matter diseases of the spinal cord cover a heterogenous group of inherited disorders, infectious and sporadic diseases. Typical examples include the spinal muscular atrophies, poliomyelitis, and motor neuron diseases. Clinical symptoms, age at onset, rate of progression, family history, and electrophysiological findings will help make the diagnosis.

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Abbreviations

ALS:

Amyotrophic lateral sclerosis

CSF:

Cerebrospinal fluid

MMA:

Monomelic amyotrophy

MND:

Motor neuron diseases

PMA:

Progressive muscular atrophy

SBMA:

Spinal and bulbar muscular atrophy

SMA:

Spinal muscular atrophy

Further Reading

  1. Chahin N, Klein C, Mandrekar J, Sorenson E (2008) Natural history of spinal-bulbar muscular atrophy. Neurology 70(21):1967–1971

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  2. Choudhary A, Sharma S, Sankhyan N, Gulati S, Kalra V, Banerjee B, Kumar A (2010) Midbrain and spinal cord magnetic resonance imaging (MRI) changes in poliomyelitis. J Child Neurol 25(4):497–499

    Article  PubMed  Google Scholar 

  3. Dejobert M, Geffray A, Delpierre C, Chassande B, Larrieu E, Magni C (2013) Hirayama disease: three cases. Diagn Interv Imaging 94(3):319–323

    Article  PubMed  CAS  Google Scholar 

  4. Finsterer J (2009) Bulbar and spinal muscular atrophy (Kennedy’s disease): a review. Eur J Neurol 16(5):556–561

    Article  PubMed  CAS  Google Scholar 

  5. Lunn MR, Wang CH (2008) Spinal muscular atrophy. Lancet 371(9630):2120–2133

    Article  PubMed  Google Scholar 

  6. Markowitz JA, Singh P, Darras BT (2012) Spinal muscular atrophy: a clinical and research update. Pediatr Neurol 46(1):1–12

    Article  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Brain Imaging Center (BIC), Department of Neurology, Goethe-University, Schleusenweg 2-16, D-60528, Frankfurt, Germany

    Johannes C. Klein

Authors
  1. Johannes C. Klein
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Correspondence to Johannes C. Klein .

Editor information

Editors and Affiliations

  1. Institute for Neuroradiology, Goethe-University, Frankfurt, Germany

    Elke Hattingen

  2. Department of Neurology, Sankt Katharinen Hospital, Frankfurt, Germany

    Stefan Weidauer

  3. Department of Neurosurgery, Goethe-University, Frankfurt, Germany

    Matthias Setzer

  4. Brain Imaging Center (BIC), Department of Neurology, Goethe-University, Frankfurt, Germany

    Johannes C. Klein

  5. H. Lee Moffitt Cancer Center, University of South Florida, Tampa, Florida, USA

    Frank Vrionis

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© 2015 Springer-Verlag Berlin Heidelberg

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Klein, J.C. (2015). Gray Matter Diseases of the Spinal Cord. In: Hattingen, E., Weidauer, S., Setzer, M., Klein, J., Vrionis, F. (eds) Diseases of the Spinal Cord. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-54209-1_17

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  • DOI: https://doi.org/10.1007/978-3-642-54209-1_17

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-54208-4

  • Online ISBN: 978-3-642-54209-1

  • eBook Packages: MedicineMedicine (R0)

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