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Pathology of Pediatric Gastrointestinal and Liver Disease pp 395–444Cite as

Diseases of the Biliary Tree

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Abstract

At The Children’s Hospital of Philadelphia, one-third of native liver biopsies are performed for the evaluation of cholestasis in the neonate and infant, and diseases of the biliary tree represent a significant group of disorders in the differential diagnosis of neonatal cholestasis. The pathologist’s role in the evaluation of biopsies in these entities is often pivotal as to the timing and need for surgical intervention and orientation of the clinical evaluation. This chapter will begin with a general overview and discussion of cholestasis in the neonate and in the older child, to be followed by a discussion of individual entities.

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Authors and Affiliations

  1. Division of Anatomic Pathology, Department of Pathology, The Children’s Hospital of Philadelphia, and The Perelman School of Medicine at The University of Pennsylvania, Philadelphia, Philadelphia, PA, 19104, USA

    Pierre Russo MD

  2. Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA

    Pierre Russo MD

  3. Department of Pediatrics, The Children’s Hospital of Philadelphia, University of Pennsylvania, 324 South 34th St., Philadelphia, PA, 19104, USA

    Elizabeth B. Rand MD

  4. Department of Pediatrics, Perelman School of Medicine at The University of Pennsylvania, The Children’s Hospital of Philadelphia, 3401 Civic Center Blvd., Philadelphia, PA, 19104, USA

    Kathleen M. Loomes MD

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  1. Pierre Russo MD
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  2. Elizabeth B. Rand MD
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  3. Kathleen M. Loomes MD
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Correspondence to Pierre Russo MD .

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Editors and Affiliations

  1. Department of Pathology, Division of Anatomic Pathology, The Children’s Hospital of Philadelphia, and the Perelman School of Medicine at The University of Pennsylvania, Philadelphia, Pennsylvania, USA

    Pierre Russo

  2. Department of Pathology, Division of Anatomic Pathology, The Children’s Hospital of Philadelphia, and the Perelman School of Medicine at The University of Pennsylvania, Philadelphia, Pennsylvania, USA

    Eduardo D. Ruchelli

  3. Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, The Children’s Hospital of Philadelphia, and the Perelman School of Medicine at The University of Pennsylvania, Philadelphia, Pennsylvania, USA

    David A. Piccoli

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Russo, P., Rand, E.B., Loomes, K.M. (2014). Diseases of the Biliary Tree. In: Russo, P., Ruchelli, E., Piccoli, D. (eds) Pathology of Pediatric Gastrointestinal and Liver Disease. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-54053-0_10

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