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Biofouling Control by Quorum Quenching

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Book cover Springer Handbook of Marine Biotechnology

Part of the book series: Springer Handbooks ((SHB))

Abstract

Bacteria above a threshold cell density regulate the expression of a specific group of their genes in response to small signal molecules called autoinducers. This twitter communication phenomenon is called quorum sensing (GlossaryTerm

QS

). Among the various genetic expressions mediated by GlossaryTerm

QS

, biofilm formation and expression of virulence factors are the most prominent. These phenotypes are a major cause of concern for health departments and a wide range of industries dealing especially with drinking water, waste water reclamation, and desalination. This phenomenon leads to heavy economic losses. Efforts to disrupt biofilms have met with little success. In fact, bacteria within the biofilms are 1000 times more resistant to antibiotics than their planktonic counterparts. Biosensors or reporter strains have been developed to screen GlossaryTerm

QS

inhibitors. A potential approach to inhibit the process of biofouling is to interfere with bacterial GlossaryTerm

QS

signals. GlossaryTerm

QS

inhibiting enzymes and molecules have been isolated from a wide range of organisms such as bacteria, fungi, algae, and marine organisms. Efforts to disrupt biofilm formation have been carried out through designing antifouling agents that primarily reduce surface adhesion of the organisms. These include fouling release coatings such as nanocomposites. In contrast to removing biofilms, there are certain areas where it is desirable to regenerate biofilm for a fresh round of biotransformation.

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Abbreviations

ACP:

acyl–acyl carrier protein

AF:

antifouling

AHL:

acyl-homoserine lactone

AttM:

lactonase of A. tumefaciens

BF:

biofouling

CEB:

cell entrapping bead

CF:

cystic fibrosis

DD:

decadienal

DNA:

deoxyribonucleic acid

DNaseI:

deoxyribonuclease

DspB:

Dispersin B

EPS:

extracellular polysaccharide

LasR:

transcriptional activator

LuxR:

transcriptional activator

MBR:

membrane bioreactor

NO:

nitric oxide

PAO:

phosphorus accumulating organism

PEG:

poly(ethylene glycol)

PIA:

polysaccharide intercellular adhesin

pyrrole-imidazole alkaloid

PNAG:

poly-N-acetyl glucosamine polysaccharide

QQ:

Quorum Quenching

QSI:

quorum sensing inhibitor

QS:

quorum sensing

RAP:

RNA III activating protein

RIP:

RNA III-inhibiting peptide

RNA:

ribonucleic acid

ROS:

reactive oxygen species

TRAP:

target of RAP

References

  1. D. Paul, Y.S. Kim, K. Ponnusamy, J.H. Kweon: Application of quorum quenching to inhibit biofilm fermentation, Environ. Eng. Sci. 26(8), 1319–1324 (2009)

    Article  CAS  Google Scholar 

  2. K.-M. Yeon, W.-S. Cheong, H.-S. Oh, W.-N. Lee, B.-K. Hwang, C.-H. Lee, H. Beyenal, Z. Lewandowski: Quorum sensing: A new biofouling control paradigm in a membrane bioreactor for advanced waste water treatment, Environ. Sci. Technol. 43(2), 380–385 (2009)

    Article  CAS  Google Scholar 

  3. S. Dobretsov, M. Teplitski, M. Bayer, S. Gunasekra, P. Proksch, V.J. Paul: Inhibition of marine biofouling by bacterial quorum sensing inhibitors, Biofouling 27(8), 893–905 (2011)

    Article  CAS  Google Scholar 

  4. M.P. Schultz, J.A. Bendick, E.R. Holm, W.M. Hertel: Economic impact of biofouling on a naval surface ship, Biofouling 27(1), 87–98 (2011)

    Article  CAS  Google Scholar 

  5. V.C. Kalia: Quorum sensing inhibitors: An overview, Biotechnol. Adv. 31(2), 224–245 (2013)

    Article  CAS  Google Scholar 

  6. V.C. Kalia, H.J. Purohit: Quenching the quorum sensing system: Potential antibacterial drug targets, Crit. Rev. Microbiol. 37(2), 121–140 (2011)

    Article  CAS  Google Scholar 

  7. S. Kappuchery, D. Paul, J. Yoon, J.H. Kweon: Vanillin, a potential agent to prevent biofouling of reverse osmosis membrane, Biofouling 26(6), 667–672 (2010)

    Article  Google Scholar 

  8. J. Landoulsi, K.E. Cooksey, V. Dupres: Review – Interactions between diatoms and stainless steel: Focus on biofouling and biocorrosion, Biofouling 27(10), 1105–1124 (2011)

    Article  CAS  Google Scholar 

  9. F.M.I. Natrah, T. Defoirdt, P. Sorgeloos, P. Bossier: Disruption of bacterial cell-to-cell communication by marine organisms and its relevance to aquaculture, Marine Biotechnol. 13(2), 109–126 (2011)

    Article  CAS  Google Scholar 

  10. K.-W. Hong, C.-L. Koh, C.-K. Sam, W.-F. Yin, K.-G. Chan: Quorum quenching revisited—from signal decays to signalling confusion, Sensors 12, 4661–4696 (2012)

    Article  Google Scholar 

  11. D.I. Sharif, J. Gallon, C.J. Smith, E. Dudley: Quorum sensing in cyanobacteria: N-octanoyl-homoserine lactone release and response, by the epilithic colonial cyanobacterium Gloethece PCC6909, ISME J. 2, 1171–1182 (2008)

    Article  CAS  Google Scholar 

  12. L. Steindler, V. Venturi: Detection of quorum-sensing N-acyl homoserine lactone signal molecules by bacterial biosensors, FEMS Microbiol. Lett. 266(1), 1–9 (2007)

    Article  CAS  Google Scholar 

  13. S.-Y. Park, H.-O. Kang, H.-S. Jang, J.-K. Lee, B.-T. Koo, D.-Y. Yum: Identification of extracellular N-acylhomoserine lactone acylase from a Streptomyces sp. and its application to quorum quenching, Appl. Environ. Microbiol. 71(5), 2632–2641 (2005)

    Article  CAS  Google Scholar 

  14. C.-N. Chen, C.-J. Chen, C.-T. Liao, C.-Y. Lee: A probable aculeacin A acylase from the Ralstoniasolanacearum GMI1000 is N-acyl-homoserine lactone acylase with quorum-quenching activity, BMC Microbiol. 9, 89 (2009)

    Article  CAS  Google Scholar 

  15. R. Chen, Z. Zhou, Y. Cao, Y. Bai, B. Yao: High yield expression of an AHL-lactonase from Bacillus sp. B546 in Pichia pastoris and its application to reduce Aeromonas hydrophila mortality in aquaculture, Microb. Cell Fact. 9, 39 (2010)

    Article  Google Scholar 

  16. N. Huma, P. Shankar, J. Kushwah, A. Bhushan, J. Joshi, T. Mukherjee, S.C. Raju, H.J. Purohit, V.C. Kalia: Diversity and polymorphism in AHL-lactonase gene (aiiA) of Bacillus, J. Microbiol. Biotechnol. 21(10), 1001–1011 (2011)

    Article  CAS  Google Scholar 

  17. V.C. Kalia, S.C. Raju, H.J. Purohit: Genomic analysis reveals versatile organisms for quorum quenching enzymes: Acyl-homoserine lactone-acylase and –lactonase, Open Microbiol. J. 5, 1–13 (2011)

    Article  CAS  Google Scholar 

  18. S. Derakhshan, M. Sattari, M. Bigdeli: Effect of cumin (Cuminum cyminum) seed essential oil on biofilm formation and plasmid integrity of Klebsiella pneumonia, Pharmacognosy Mag. 6(21), 57–61 (2010)

    Article  CAS  Google Scholar 

  19. S.K. Musthafa, A.V. Ravi, A. Annapoorani, I.S.V. Packiavathy, S.K. Pandian: Evaluation of anti-quorum-sensing activity of edible plants and fruits through inhibition of the N-acyl-homoserine lactone system in Chromobacterium violaceum and Pseudomonas aeruginosa, Chemotherapy 56(4), 333–339 (2010)

    Article  CAS  Google Scholar 

  20. T. Krishnan, W.F. Yin, K.G. Chan: Inhibition of quorum sensing-controlled virulence factor production in Pseudomonas aeruginosa PAO1 by Ayurveda spice clove (Syzygium aromaticum) bud extract, Sensors (Basel) 12(4), 4016–4030 (2012)

    Article  CAS  Google Scholar 

  21. I.S.V. Packiavathy, P. Agilandeswari, K.S. Musthafa, S.K. Pandian, A.V. Ravi: Antibiofilm and quorum sensing inhibitory potential of Cuminum cyminum and its secondary metabolite methyl eugenol against Gram negative bacterial pathogens, Food Res. Int. 45, 85–92 (2012)

    Article  CAS  Google Scholar 

  22. S. Dobrestov, H.U. Dahms, P.Y. Qian: Inhibition of biofouling by marine microorganisms and their metabolites, Biofouling 22(1), 43–54 (2006)

    Article  Google Scholar 

  23. R. Thenmozhi, P. Nithyanand, J. Rathna, S.K. Pandian: Antibiofilm activity of coral-associated bacteria against different clinical M serotypes of Streptococcus pyogenes, FEMS Immunol. Med. Microbiol. 57(3), 284–294 (2009)

    Article  CAS  Google Scholar 

  24. D. Bakkiyaraj, S.K. Pandian: In vitro and in vivo antibiofilm activity of a coral associated actinomycete against drug resistant Staphylococcus aureus biofilms, Biofouling 26(6), 711–717 (2010)

    Article  CAS  Google Scholar 

  25. C. Nithya, S.K. Pandian: The in vitro antibiofilm activity of selected marine bacterial culture supernatants against Vibrio spp, Arch. Microbiology 192(10), 843–854 (2010)

    Article  CAS  Google Scholar 

  26. C. Nithya, C. Arvindraja, S.K. Pandian: Bacillus pumilus of Palk Bay origin inhibits quorum-sensing-mediated virulence factors in Gram-negative bacteria, Res. Microbiology 161(4), 293–304 (2010)

    Article  CAS  Google Scholar 

  27. C. Nithya, M.F. Begum, S.K. Pandian: Marine bacterial isolates inhibit biofilm formation and disrupt mature biofilms of Pseudomonas aeruginosa PAO1, Appl. Microbiol. Biotechnol. 88(1), 341–358 (2010)

    Article  CAS  Google Scholar 

  28. C. Nithya, M.G. Devi, S.K. Pandian: A novel compound from the marine bacterium Bacillus pumilus S6-15 inhibits biofilm formation in Gram-positive and Gram-negative species, Biofouling 27(5), 519–528 (2011)

    Article  CAS  Google Scholar 

  29. K.S. Musthafa, V. Saroja, S.K. Pandian, A.V. Ravi: Antipathogenic potential of a marine Bacillus sp. SS4 on N-acyl-homoserine-lactone-mediated virulence factors production in Pseudomonas aeruginosa(PAO1), J. Bioscience 36(1), 55–67 (2011)

    Article  CAS  Google Scholar 

  30. A. Annapoorani, A.K.K.A. Jabbar, S.K.S. Musthafa, S.K. Pandian, A.V. Ravi: Inhibition of quorum sensing mediated virulence factors production in urinary pathogen Serratia marcescens PS1 by marine sponges, Indian J. Microbiol. 52(2), 160–166 (2012)

    Article  Google Scholar 

  31. S.D. Stowe, J.J. Richards, A.T. Tucker, R. Thompson, C. Melander, J. Cavanagh: Anti-biofilm compounds derived from marine sponges, Mar. Drugs 9(10), 2010–2035 (2011)

    Article  CAS  Google Scholar 

  32. E.M. Hetrick, J.H. Shin, N.A. Stasko, C.B. Johnson, D.A. Wespe, E. Holumuhamedov, M.H. Schoenfisch: Bacterial efficacy of nitric oxide-releasing silica nanoparticles, ACS Nano 2(2), 235–246 (2008)

    Article  CAS  Google Scholar 

  33. E.M. Hetrick, J.H. Shin, H.S. Paul, M.H. Schoenfisch: Anti-biofilm efficacy of nitric oxide-releasing silica nanoparticles, Biomaterials 30(14), 2782–2789 (2009)

    Article  CAS  Google Scholar 

  34. A.J. Scardino, R. de Nys: Biomimetic models and bioinspired surfaces for fouling control, Biofouling 27(1), 73–86 (2011)

    Article  CAS  Google Scholar 

  35. E. Martinelli, M. Suffredini, G. Galli, A. Glisenti, M.E. Pettitt, M.E. Callow, J.A. Callow, D. Williams, G. Lyall: Amphiphillic block copolymer/poly(dimethylsiloxane) (PDMS) blends and nanocomposites for improved fouling-release, Biofouling 27(5), 529–541 (2011)

    Article  CAS  Google Scholar 

  36. J.B. Kristensena, R.L. Meyer, B.S. Laursen, S. Shipovskov, F. Besenbacher, C.H. Poulsena: Antifouling enzymes and the biochemistry of marine settlement, Biotechnology Adv. 26(5), 471–481 (2008)

    Article  Google Scholar 

  37. B.R. Boles, A.R. Horswill: Staphylococcal biofilm disassembly, Trends Microbiol. 19(9), 449–455 (2011)

    Article  CAS  Google Scholar 

  38. C.R. Arciola, L. Montanaro, J.W. Costerton: New trends in diagnosis and control strategies for implant infections, Int. J. Artif. Organs 34(9), 727–736 (2011)

    Article  CAS  Google Scholar 

  39. C.E. Marcato-Romain, Y. Pechaud, E. Paul, E. Girbal-Neuhauserand, V. Dossat-Létisse: Removal of microbial multi-species biofilms from the paper industry by enzymatic treatments, Biofouling 28(3), 305–314 (2012)

    Article  CAS  Google Scholar 

  40. C. Leroy, C. Delbarre, F. Ghillebaert, C. Compere, D. Combes: Effects of commercial enzymes on the adhesion of a marine biofilm-forming bacterium, Biofouling 24(1), 11–22 (2008)

    Article  CAS  Google Scholar 

  41. A.D. Leslie: Preventing biofilm formation using microbes and their enzymes, Basic Biotechnol. 7, 6–11 (2011)

    Google Scholar 

  42. T.K. Lu, J.J. Collins: Dispersing biofilms with engineered enzymatic bacteriophage, Proc. Natl. Acad. Sci. USA 104(27), 11197–11202 (2007)

    Article  CAS  Google Scholar 

  43. S.H. Hong, M. Hegde, J. Kim, J. Wang, A. Jayaram, T.K. Wood: Synthetic quorum-sensing circuit to control consortial biofilm formation and dispersal in a microfluidic device, Nature Commun. 3, 613 (2012)

    Article  Google Scholar 

  44. S.R. Kim, H.S. Oh, S.J. Jo, K.M. Yeon, C.H. Lee, D.J. Lim, C.H. Lee, J.K. Lee: Biofouling control with bead-entrapped quorum quenching bacteria in membrane bioreactors: physical and biological effects, Environ. Sci. Technol. 47(2), 836–842 (2013)

    Article  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Microbial Biotechnology and Genomics, CSIR-Institute of Genomics and Integrative Biology, 110007, Delhi, India

    Vipin C. Kalia

  2. Microbial Biotechnology and Genomics, CSIR-Institute of Genomics and Integrative Biology, 110007, Delhi, India

    Prasun Kumar

  3. Department of Biotechnology, Alagappa University, Science Campus, 630003, Karaikudi, Tamil Nadu, India

    Shunmughiah T. K. Pandian

  4. Department of Microbiology, Panjab University, 160014, Chandigarh, India

    Prince Sharma

Authors
  1. Vipin C. Kalia
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  2. Prasun Kumar
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  3. Shunmughiah T. K. Pandian
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  4. Prince Sharma
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Corresponding author

Correspondence to Vipin C. Kalia .

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Editors and Affiliations

  1. Department of Marine-Bio. Convergence Science Specialized Graduate School Science & Technology Convergence Marine Bioprocess Research Center, Pukyong National University, Yongdang Campus, 365, Sinseon-ro, Nam-gu, 608-739, Busan, Korea

    Se-Kwon Kim Prof.

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Kalia, V.C., Kumar, P., Pandian, S.T.K., Sharma, P. (2015). Biofouling Control by Quorum Quenching. In: Kim, SK. (eds) Springer Handbook of Marine Biotechnology. Springer Handbooks. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-53971-8_15

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