Abstract
Increased drug resistance in pathogenic microorganisms, leading to a decrease in the effectiveness of antibiotic, antiviral, antiparasitic and antifungal therapy, has generated international concern. This has triggered numerous studies seeking alternative antimicrobial technologies independent of pharmacology, which resulted in success in therapeutic protocols. One of the most important examples of these innovations is antimicrobial photodynamic therapy. Since the beginning of the last century, the combined use of light and dyes has been used to eliminate microorganisms. However, this therapy was forgotten after the discovery of antibiotics in the 1950s and is returning to the research field today. Numerous studies have shown that photodynamic therapy is an effective way to eliminate microorganisms, especially those that cause infections, including those in the oral cavity. However, it is important to realise that many infectious diseases will continue to need systemic therapy. The rapid growth in the use of photodynamic therapy during recent years in dentistry illustrates the number of infections that can be treated medically in this manner in the future.
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Silva, M.P., Junqueira, J.C., Jorge, A.O.C. (2014). The Effects of Photodynamic Therapy in Oral Biofilms. In: Rumbaugh, K., Ahmad, I. (eds) Antibiofilm Agents. Springer Series on Biofilms, vol 8. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-53833-9_20
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