Abstract
While the knowledge of the blood sugar lowering properties of the sulphonamide derivatives have been available for 20 years, the hypoglycaemic effect of guanidine was already known before insulin was discovered. The attempt performed 30 years ago in troducing synthalin, a derivative of guanidine, in diabetes mellitus therapy failed. Another derivative of guanidine—phenylaethylbiguanide (DBI) — has been increasingly used in diabetes therapy especially in the States, for the last 3 years.
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© 1961 Springer-Verlag OHG. Berlin · Göttingen · Heidelberg
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Creutzfeldt, W., Söling, HD. (1961). Guanidine and guanidine derivatives. In: Oral Treatment of Diabetes. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-52692-3_3
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DOI: https://doi.org/10.1007/978-3-642-52692-3_3
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-52693-0
Online ISBN: 978-3-642-52692-3
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