Zusammenfassung
Das Bindegewebe ist das Zielorgan verschiedener Erkrankungen des kardiovaskulären Systems. Zahlreiche Befunde sprechen für eine Beteiligung der Proteoglycane der Extrazellulärmatrix an der Pathogenese der Arteriosklerose.
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Abbreviations
- CS:
-
Chondroitinsulfat
- DS:
-
Dermatansulfat
- GAG:
-
Glycosaminoglycan
- HS:
-
Heparansulfat
- KS:
-
Keratansulfat
- PG:
-
Proteoglycan
- IL:
-
Interleukin
- TGF-ß:
-
transformierender Wachstumsfaktor ß
- bFGF:
-
basischer FibroblastenWachstumsfaktor
- TNF:
-
Tumornekrose-Faktor
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Greiling, H., Haubeck, HD., Stöcker, G., Stuhlsatz, H.W. (1994). Zur Pathobiochemie der extrazellulären Matrix des kardiovaskulären Systems. In: Greiling, H., Neumann, S. (eds) Pathobiochemie, Molekularbiologie und moderne Diagnostik kardiovaskulärer Erkrankungen. Zusammenarbeit von Klinik und Klinischer Chemie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-52362-5_4
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