Abstract
Vascular response to changes in arterial CO2 content can be evaluated by analysis of Doppler curves in the middle cerebral artery (MCA). This analysis enables calculation of vascular reactivity which indicates the capability of the cerebrum of controling peripheral vascular resistance. In patients with threatening cerebrovascular disease (CVD) this capability may be reduced by inadequate vascular autoregulation. It appears that changes of blood flow in the Circle of Willis play an important role in the pathophysiology of vascular autoregulation in patients with CVD. Furthermore, our data suggest that the previously used classifications of CVD (degree of stenosis, clinical stage) allow neither precise description of the actual pathophysiology nor exact prognosis of CVD.
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© 1990 Springer-Verlag Berlin Heidelberg
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Furst, H., Trautvetter, D., Hartl, W.H., Schildberg, F.W. (1990). Analysis of Transcranial Doppler Waves: Pathophysiology of Unilateral Stenoses of the Carotid Artery. In: Liepsch, D.W. (eds) Biofluid Mechanics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-52338-0_3
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DOI: https://doi.org/10.1007/978-3-642-52338-0_3
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