Abstract
The risk of death from major cardiovascular events is related to the level of resting blood pressure. However, the mechanisms by which atherosclerosis is accelerated in patients with essential hypertension are unknown. Abnormalities of lipid metabolism or of platelet function are seemingly not a feature of hypertension. The distribution of atherosclerotic plaques in the arteries implies an important role in atherogenesis for mechanical factors such as arterial wall mass transport and blood flow and shear stress patterns [1,2]. Structural and mechanical changes in the arterial wall are features of essential hypertension [3] and may alter vascular fluid mechanics in patients with hypertension. We describe studies which we have undertaken to test this hypothesis [4]. Such alterations may be relevant to the development of atheroma.
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© 1990 Springer-Verlag Berlin Heidelberg
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Jones, C.J.H., Caro, C.G. (1990). The Potential Importance of Arterial Wall Properties and Blood Flow in Relation to Atherogenesis in Essential Hypertension. In: Liepsch, D.W. (eds) Biofluid Mechanics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-52338-0_12
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DOI: https://doi.org/10.1007/978-3-642-52338-0_12
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