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Toxische Nierenschäden

  • E. Heidbreder
  • A. Heidland
Conference paper
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Part of the Advances in Internal Medicine and Pediatrics / Ergebnisse der Inneren Medizin und Kinderheilkunde book series (KINDERHEILK. NF, volume 59)

Zusammenfassung

Das funktionstragende Element der Niere ist das Nephron, dessen Vielzahl ein komplexes System filtrierender, reabsorbierender und sezernierender Strukturen bildet. Das initiale Glied der Harnbereitung sind vaskuläre Elemente, das Glomerulum sowie das Vas afferens und das Vas efferens; zwischen ihnen sind die den Primärharn filtrierenden Glomerula eingeschaltet (Abb. 1). Über sie gelangen Stoffe einerseits zum Tubulus, wo sie sezerniert werden, andererseits transportieren sie andere und reabsorbierte Stoffe in den großen Kreislauf zurück. Die Glomerula liegen in der Nierenrinde; je nach Lage — oberflächlich (superfizial) oder marknahe (juxtaglomerulär) — sind ihre tubulären Schleifen lang oder kurz (Abb. 2). Jeder Nephronabschnitt hat seine spezifische Funktion, sie kann jeweils substanzspezifisch durch verschiedene Toxine alteriert werden.

Key Words

Nephrotoxische Substanzen akutes Nierenversagen interstitielle Nephritis Glomerulonephritis Vaskulitits tubuläre Funktionsstörungen 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • E. Heidbreder
  • A. Heidland
    • 1
  1. 1.LuitpoldkrankenhausMedizinische UniversitätsklinikWürzburgGermany

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