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Immunology and Epidemiology pp 229–242Cite as

Application of Mathematical Models in the Membrane Electrophysiology of Macrophages

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Part of the book series: Lecture Notes in Biomathematics ((LNBM,volume 65))

Abstract

In most cells there is a transmembrane potential difference, called a resting membrane potential (about -70 mV) arising from the unequal distributions of ions across the cell membrane and the selective permeability of the cell membrane for the various ion species. In nerve and muscle cells a sudden change in the ionic permeability of the membrane causes a rapid all-or-nothing change in membrane potential called an action potential. In nerve cells the action potential forms the basic information-carrying signal and in muscles cells it evokes cell contraction (27).

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Author information

Authors and Affiliations

  1. Department of Infectious Diseases, University Hospital, 2333 AA, Leiden, The Netherlands

    Can Ince

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  1. Can Ince
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Editors and Affiliations

  1. Departments of Physics and Microbiology, The University of British Columbia, Vancouver, B.C., V6T 1W5, Canada

    Geoffrey W. Hoffmann

  2. Institute of Molecular Genetics, Czechoslovak Academy of Sciences, 142 20, Prague, Czechoslavakia

    Tomáš Hraba

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© 1986 Springer-Verlag Berlin Heidelberg

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Ince, C. (1986). Application of Mathematical Models in the Membrane Electrophysiology of Macrophages. In: Hoffmann, G.W., Hraba, T. (eds) Immunology and Epidemiology. Lecture Notes in Biomathematics, vol 65. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-51691-7_15

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  • DOI: https://doi.org/10.1007/978-3-642-51691-7_15

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-16431-9

  • Online ISBN: 978-3-642-51691-7

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