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Ca-Mg Control of Ciliary Motion: A Quantitative Model Study

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Biological Motion

Part of the book series: Lecture Notes in Biomathematics ((LNBM,volume 89))

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Abstract

We have developed a generalized model for Ca-mediated control of ciliary beating using established data from the literature. According to the model, both direction and frequency of beating are controlled by membrane-regulated Ca2+ as the intraciliary messenger including a modulatory function of Mg2+ which competes with Ca2+ for binding to an axonemal protein.

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References

  • Bonini N.M. and Nelson D.L. (1988) Differential regulation of Paramecium ciliary motility by cAMP and cGMP. J. Cell Biol. 106: 1615–1623

    Article  Google Scholar 

  • Bonini N.M., Gustin M.C. and Nelson D.L. (1986) Regulation of ciliary motility by membrane potential in Paramecium: a role for cyclic AMP. Cell Motility Cytoskel. 6: 256–272

    Article  Google Scholar 

  • Brokaw C.J., Josslin R. and Bobrow L. (1974) Calcium ion regulation of flagellar beat symmetry in reactivated sea urchin spermatozoa. Biochem. Biophys. Res. Commun. 58: 795–800

    Article  Google Scholar 

  • Hennessey Т., Machemer H. and Nelson D.L. (1985) Injected cyclic AMP increases ciliary beat frequency in conjunction with membrane hyperpolarization. Eur. J. Cell Biol. 36: 153–156

    Google Scholar 

  • Izumi A. and Nakaoka Y. (1987) cAMP-mediated inhibitory effect of calmodulin antagonists on ciliary reversal of Paramecium. Cell Motility Cytoskel. 7: 154–159

    Article  Google Scholar 

  • Machemer H. (1974) Frequency and directional responses of cilia to membrane potential changes in Paramecium. J. Comp. Physiol. 92: 293–316

    Article  Google Scholar 

  • Machemer H. (1976) Interactions of membrane potential and cations in regulation of ciliary activity in Paramecium. J. Exp. Biol. 65: 427–448

    Google Scholar 

  • Machemer H. (1986) Electromotor coupling in cilia. In: H.C. Lüttgau (Edit) Membrane control of cellular activity. Fortschr. Zool. 33: 205–250

    Google Scholar 

  • Machemer H. and De Peyer J.E. (1982) Analysis of ciliary beating frequency under voltage-clamp control of the membrane. Cell Motility (Suppl.) 1: 205–210

    Article  Google Scholar 

  • Naitoh Y. and Kaneko H. (1972) Reactivated Triton-extracted models of Paramecium: modification of ciliary movements by calcium ions. Science 176: 523–524

    Article  Google Scholar 

  • Naitoh Y. and Kaneko H. (1973) Control of ciliary activity by adenosinetriphosphate and divalent cations in Triton-extracted models of Paramecium caudatum. J. Exp. Biol. 58: 657–676

    Google Scholar 

  • Nakaoka Y. and Machemer H. (1990) Effects of cyclic nucleotides and intracellular Ca2+ on voltage-activated ciliary beating in Paramecium J. Comp. Physiol. A 166: 401–406

    Article  Google Scholar 

  • Nakaoka Y. and Toyotama H. (1979) Directional change of ciliary beat effected with Mg2+ in Paramecium. J. Cell Sci. 40: 207–214

    Google Scholar 

  • Nakaoka Y., Tanaka, H. and Oosawa F. (1984) Ca2+-dependent regulation of beat frequency of cilia in Paramecium. J. Cell Sci. 65: 223–231

    Google Scholar 

  • Potter J.D., Strang-Brown P., Walker P.L. and Iida S. (1983) Ca2+ binding to calmodulin. Methods Enzymol. 102: 135–143

    Article  Google Scholar 

  • Schultz J.E., Grünemund R., von Hirschhausen R. and Schönefeld U. (1984) Ionic regulation of cyclic AMP levels in Paramecium tetraurelisa. FEBS Lett., 167: 113–116

    Article  Google Scholar 

  • Brokaw C.J. (1974) Movement of the flagellum of some marine invertebrate spermatozoa: 93–109. In: M.A. Sleigh (ed.) Cilia and flagella. Academic Press, London, New York

    Google Scholar 

  • Gibbons I.R. (1975) The molecular basis of flagellar motility in sea urchin spermatozoa: 207–231. In: S. Inoué and R.E. Stephens (eds.) Molecules and cell movement. Raven Press, New York

    Google Scholar 

  • Hines M. and Blum J.J. (1985) On the contribution of dynein-like activity to twisting in a three-dimensional sliding filament model. Biophys. J. 47: 705–708

    Article  Google Scholar 

  • Ishijima S. and Mohri H. (1985) A quantitative description of flagellar movement in golden hamster spermatozoa. J. Exp. Biol. 114: 463–475

    Google Scholar 

  • Machemer H. (1972a) Properties of polarized ciliary beat in Paramecium. Acta Protozool. 11: 295–300

    Google Scholar 

  • Machemer H. (1972b) Ciliary activity and the origin of meta-chrony in Paramecium: Effects of increased viscosity. J. Exp. Biol. 57: 239–259

    Google Scholar 

  • Machemer H. (1977) Motor activity and bioelectric control of cilia. Fortschr. Zool. 24: 195–210

    Google Scholar 

  • Machemer H. and Eckert R. (1975) Ciliary frequency and orien-tational responses to clamped voltage steps in Paramecium. J. Comp. Physiol. 104: 247–260

    Article  Google Scholar 

  • Machemer H. and Eckert R. (1977) Electromechanical coupling of ciliary activity in Paramecium. Fortschr. Zool. 24: 211–215

    Google Scholar 

  • Machemer H, and Sugino K. (1986) Parameters of the ciliary cycle under membrane voltage control. Cell Motility Cytoskel. 6: 89–95

    Article  Google Scholar 

  • Omoto C.K. and Brokaw C.J. (1983) Quantitative analysis of axonemal bends and twists in the quiescent state of Ciona sperm flagella. Cell Motility 3: 247–259

    Article  Google Scholar 

  • Pape H.C. and Machemer H. (1986) Electrical properties and membrane currents in the ciliate Didinium. J. Comp. Physiol. A 158: 111–124

    Article  Google Scholar 

  • Pitelka D. (1968) Fibrillar systems in protozoa: 280–388. In: T.T. Chen (ed.) Research in protozoology. Pergamon Press, Oxford

    Google Scholar 

  • Sale W.S. and Satir P. (1977) Direction of active sliding of microtubules in Tetrahymena cilia. Proc. Natl. Acad. Sci. USA 74: 2045–2049

    Article  Google Scholar 

  • Satir P. (1985) Switching mechanisms in the control of ciliary motility. Modern Cell Biology 4: 1–46

    Google Scholar 

  • Satir P., Wais-Steider J., Lebduska S., Nasr A. and Avolio J. (1981) The mechanochemical cycle of the dynein arm. Cell Motility 1: 303–327

    Article  Google Scholar 

  • Sugino K. and Machemer H. (1987) Axial-view recording: An approach to assess the third dimension of the ciliary cycle. J. Theor. Biol. 125: 67–82

    Article  Google Scholar 

  • Sugino K. and Machemer H. (1990) Depolarization-controlled parameters of the ciliary cycle and axonemal function. Cell Motil. Cytoskeleton 16: (in press)

    Google Scholar 

  • Sugino K. and Naitoh Y. (1982) Simulated cross-bridge patterns corresponding to ciliary beating in Paramecium. Nature 295: 609–611

    Article  Google Scholar 

  • Tamm S.L. and Tamm S. (1981) Ciliary reversal without rotation of axonemal structures in ctenophore comb plates. J. Cell Biol. 89: 495–509

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. Arbeitsgruppe Zelluläre Erregungsphysiologie, Fakultät für Biologie, Ruhr-Universität, D-4630, Bochum 1, Federal Republic of Germany

    Yoshihiro Mogami & Hans Machemer

Authors
  1. Yoshihiro Mogami
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  2. Hans Machemer
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Editor information

Editors and Affiliations

  1. Abteilung Theoretische Biologie, Universität Bonn, 5300, Bonn, Germany

    Wolfgang Alt

  2. Zoologisches Institut II, Universität Würzburg, 8700, Würzburg, Germany

    Gerhard Hoffmann

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© 1990 Springer-Verlag Berlin Heidelberg

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Mogami, Y., Machemer, H. (1990). Ca-Mg Control of Ciliary Motion: A Quantitative Model Study. In: Alt, W., Hoffmann, G. (eds) Biological Motion. Lecture Notes in Biomathematics, vol 89. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-51664-1_13

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  • DOI: https://doi.org/10.1007/978-3-642-51664-1_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-53520-1

  • Online ISBN: 978-3-642-51664-1

  • eBook Packages: Springer Book Archive

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