Zusammenfassung
Der Begriff der Regeneration umfaßt den Ersatz von verloren gegangenen, experimentell entfernten oder funktionsuntüchtig gewordenen Organen, Geweben, Zellen oder Zellbestandteilen. Im erwachsenen Organismus erlauben Regenerationsvorgänge eine Normalisierung von Funktionen, die durch physiologische oder pathologische Prozesse gestört oder gefährdet sind. Im allgemeinen wird dabei in funktioneller und morphologischer Hinsicht eine Rückkehr zum Status quo ante angestrebt. Bei der Analyse von Regenerations Vorgängen erhebt sich deshalb die Frage nach den Regulationsmechanismen, die die Zunahme lebender Masse auslösen und ihr Ausmaß bestimmen, so daß das funktionelle Gleichgewicht innerhalb des Gesamtorganismus wiederhergestellt wird (Bullough 1962, Teir und RytÖmaa 1967, F. F. Becker 1969). Diese Regulationsmechanismen sind offensichtlich im molekularen Geschehen verankert, und zu ihrer Aufklärung werden wohl vor allem biochemische Untersuchungsmethoden herangezogen werden müssen. Biochemische Prozesse während Regenerationsvorg ängen sind deshalb in erster Linie hinsichtlich der beteiligten Regulationsmechanismen von Interesse.
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Bern, R.S. (1969). Biochemie der Regeneration. In: Calvo, W., et al. Entwicklung · Wachstum II. Handbuch der Allgemeinen Pathologie, vol 6 / 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-51627-6_1
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DOI: https://doi.org/10.1007/978-3-642-51627-6_1
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