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Mechanisms of ventilation-perfusion mismatch and hemodynamic alterations in acute and chronic pulmonary embolism

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Acute Pulmonary Embolism

Summary

Studies on gas exchange in pulmonary embolism are not numerous. A few of them have been performed in experimental animals [4]. The methods employed comprise the determination of gas exchange parameters [14], including the physiologic dead space [1], and the multiple inert gas elimination technique [2,8,10].

Furthermore, not much effort has been made to relate topographical alterations of ventilation and blood flow, detected by external counting of radioactive tracers, to ventilation/perfusion (V̊A/Q̊) disturbances responsible for impaired gas exchange in pulmonary embolism.

This paper reports data on pulmonary gas exchange, V̊A/Q̊ distribution by inert gas elimination, and regional lung function by ventilation and perfusion scan in human pulmonary embolism.

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© 2000 Dr. Dietrich Steinkopff Verlag GmbH & Co. KG, Darmstadt

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Giuntini, C. et al. (2000). Mechanisms of ventilation-perfusion mismatch and hemodynamic alterations in acute and chronic pulmonary embolism. In: Geibel, A., Just, H., Kasper, W., Konstantinides, S. (eds) Acute Pulmonary Embolism. Steinkopff. https://doi.org/10.1007/978-3-642-51190-5_4

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  • DOI: https://doi.org/10.1007/978-3-642-51190-5_4

  • Publisher Name: Steinkopff

  • Print ISBN: 978-3-642-51192-9

  • Online ISBN: 978-3-642-51190-5

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