Abstract
Investigations on recovery from sublethal and potentially lethal damage in cultured mammalian cells and microorganisms are reviewed and some new experimental results with yeast presented. The processes of recovery from sublethal and potentially lethal damage are not necessarily qualitatively different although they appear to be antagonistic in several repects. A model is developed, whose basic features are: after irradiation two processes enter into competition, viz. damage repair and damage fixation, both of which may be influenced differently by certain treatments. The experimental results are discussed in terms of the model suggested.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Achey, P. M., and E. C. Pollard: Rad. Res. 31, 47 (1967).
Alper, T.: Discussion remarks in: Repair from genetic radiation demage, (F. Sobels, Ed.), p. 120. Oxford-London-New York-Paris 1963.
Bacchetti, S.: Int. J. Radiat. Biol. 10, 213 (1966).
Bacchetti, S.: Rad. Res. 29, 295 (1966).
Bacchetti, S., M. Cassandro and F. Mauro: Exp. Cell. Res. 46, 292 (1967).
Bacq, Z. M., and P. Alexander: Fundamentals of Radiobiology. Oxford: Pergamon Press 1961.
Bedford, J. S., and E. J. Hall: Int. J. Radiat. Biol. 7, 377 (1963).
Berry, R. J., and R. Oliver: Nature (London) 201, 94 (1964).
Cleaver, J. E.: Biochem. Biophys. Res. Comm. 24, 569 (1966).
Elkind, M. M., and H. Sutton: Nature (London) 184, 1293 (1959).
Elkind, M. M., and H. Sutton: Rad. Res. 13, 556 (1960).
Elkind, M. M., G. F. Whitmore and T. Alescio: Science 143, 1454 (1964).
Elkind, M. M., and T. Alescio, W. B. Moses and H. Sutton: Rad Res. 22, 186 (1964).
Elkind, M. M., H. Sutton-Gilbert, W. B. Moses, T. Alescio and R. W. Swain: Rad. Res. 25, 359 (1965).
Elkind, M. M., W. Sinclair: In: Current topics in Radiation Research (M. Ebert and A. Howard, Eds.), p. 165. Vol. I, Amsterdam 1965.
Elkind, M. M., In: Radiation Research (G. Silini, Ed.), p. 558. Amsterdam 1967.
Evans, H. J.: In: Radiation Research (G. Silini, Ed.), p. 482. Amsterdam 1967.
Freeman, K. S., and D. Halder: Biochem. Biophys. Res. Comm. 28, 8 (1967).
Gillies, N. E., and T. Alper: Nature (London) 183, 237 (1959).
Goldberg, I. H., and M. Rabinowitz: Science 136, 315 (1962).
Han, A., N. Miletic and D. Petrovic: Int. J. Radiat. Biol. 8, 187 (1965).
Harm, W.: Rad. Res. 31, 548 (1967).
Hornsey, S., and S. Vatistas: Brit. J. Radiol. 36, 795 (1963).
Howard-Flanders, P., and P. T. Emmerich: Biochem. Biophys. Res. Comm. 18, 24 (1965).
Hug, O., u. A. Kellerer: Stochastik der Strahlenwirkung. Berlin-Heidelberg-New York: Springer 1966.
Kallmann, R. J.: Nature (London) 197, 557 (1963).
Kaplan, H. S., K. C. Smith and P. A. Tomlin: Rad. Res. 16, 98 (1962).
Kapulzevich, U. H., and V. J. Korogodin: Radiobiologiya (Moscow) 4, 349 (1964).
Kelner, A.: Proc. Nat. Acad. Sci., U.S. 35, 73 (1949).
Kiefer, J.: Naturwissenschaften 51, 289 (1964).
Kiefer, J.: Int. J. Radiat. Biol. 11, 373 (1966).
Kiefer, J.: Helgol. wiss. Meeresuntersuchungen 14, 195 (1966).
Kiefer, J.: to be published.
Kiefer, J.: to be published.
Kim, J. H., M. L. Eidinoff and J. S. Laughlin: Nature (London) 204, 598 (1964).
Korogodin, V. J.: Biol. Med. (Paris) 65, 402 (1965).
Korogodin, V. J.: Problems of postirradiation recovery. Moscow 1966.
Korogodin, V. J., V. J. Meissel and T. S. Remesova: In: Radiation Research (G. Silini, Ed.), p. 538. Amsterdam 1967.
Muhammed, A.: J. Biol. Chem. 241, 516 (1966).
Olivera, B. M., and I.R. Lehman: Proc. Nat. Acad. Sci. U. S. 57, 1701 (1967).
Patrick, M. H., R. H. Haynes and R. B. Uretz: Rad. Res. 21, 144 (1964).
Patrick, M. H., R. H. Haynes and R. B. Uretz: Rad. Res. 23, 564 (1964).
Pettijohn, D., and P. C. Hanawalt: J. Mol. Biol. 9, 395 (1964).
Phillips, R. A., and L. J. Tolmach: Rad. Res. 29, 413 (1966).
Rörsch, R., P. van de Putte, I. E. Mattern, H. Zwenk and C. A. van Sluis: In: Radiation Research (G. Silini, Ed.), p. 771. Amsterdam 1967.
Rosenberg, B. H., and L. F. Cavelieri: Nature 206, 999 (1965).
Setlow, I.: in: Current topics in Radiation Research (M. Ebert and A. Howard, Eds.), Vol. II, p. 195. Amsterdam 1967.
Sommer, N. F., J. H. Görtz and E. C. Maxie: Rad. Res 24, 390 (1965).
Stapleton, G. E., D. Billen and A. Hollaender: J. Cell. Comp. Physiol. 41, 345 (1953).
Weiss, B., T. R. Live and C. C. Richardson: Feder. Proc. 26, 395 (1967).
Winkler, U.: In: Radiation Research, (G. Silini, Ed.) p. 796. Amsterdam 1967.
Witkin, E.: In: Repair from genetic radiation damage, (F. Sobels, Ed.) p. 151. Oxford-London-New York-Paris 1963.
Whitmore, G. F.: Paper at the 3rd. Congress of Radiation Research Cortina (Italy) 1966.
Zimmer, K. G.: Quantitative Radiobiology. Edinburgh: Oliver and Boyd 1961.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1968 Springer-Verlag Berlin · Heidelberg
About this paper
Cite this paper
Kiefer, J. (1968). Intracellular Recovery after Irradiation. In: Locker, A. (eds) Quantitative Biology of Metabolism. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-51065-6_24
Download citation
DOI: https://doi.org/10.1007/978-3-642-51065-6_24
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-04301-0
Online ISBN: 978-3-642-51065-6
eBook Packages: Springer Book Archive