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Superantigens pp 1–19Cite as

Molecular Genetics of Pyrogenic Exotoxin “Superantigens” of Group A Streptococci and Staphylococcus aureus

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Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 174))

Abstract

Many bacteria require a complex set of host-parasite interactions in order to cause disease. Perhaps the most straightforward of these interactions is elaboration by the microbe of toxins which induce disease manifestations. In this example the pathogen must only be able to survive and multiply within the host for a sufficient period of time to make the toxin. Toxin-host cell receptor interactions then determine the extent of host tissue damage.

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Authors and Affiliations

  1. Department of Microbiology, University of Minnesota Medical School, Box 196 UMHC, 420 Delaware Street Southeast, Minneapolis, MN, 55455, USA

    P. K. Lee & P. M. Schlievert

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  1. P. K. Lee
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  2. P. M. Schlievert
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Editors and Affiliations

  1. Pathophysiology Section, First Department of Medicine, University of Mainz, 6500, Mainz, Germany

    Bernhard Fleischer

  2. Wallenberg Laboratory, University of Lund, 22007, Lund, Sweden

    Hans Olov Sjögren

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Lee, P.K., Schlievert, P.M. (1991). Molecular Genetics of Pyrogenic Exotoxin “Superantigens” of Group A Streptococci and Staphylococcus aureus . In: Fleischer, B., Sjögren, H.O. (eds) Superantigens. Current Topics in Microbiology and Immunology, vol 174. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-50998-8_1

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  • DOI: https://doi.org/10.1007/978-3-642-50998-8_1

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