Experimental and First Clinical Results of Nd:YAG Laser-Induced Interstitial Hyperthermia in Brain Tumours
Interstitial thermotherapy using a low power Nd:YAG laser is a new therapeutic approach in the treatment of malignant gliomas. The 1.06 um Nd:YAG laser is an excellent source of local hyperthermia because of its good coagulative properties, its relatively low abcorption in brain tissuc and its transmission by an optic fibre. A specially designed laser light guide, the Interstitial Thermotherapy (ITT) laser fibre, is connected to the Nd:YAG laser and inserted stereotactically in brain tumours. The quartz glass cap at the fibre tip requires no irrigation medium and allows transmission of laser energy up to 10 W, which is sufficient for local hyperthermia.
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- 1.Ascher PW (1990) Interstitial thermal therapy for brain tumors with Nd:YAG laser under real time MRI control. In: Joffe SN, Attsum K (eds) Proceedings of laser surgery: advanced characterization, therapeutics and systems II, SPIE, vol. 1200, pp 242–246Google Scholar
- 2.Bettag M, Ulrich F, Fürst G, Langen K-J, Roosen N, Kiwit JCW, Hessel S, Mödder U, Bock WJ (1991) Gadolinium-DTPA enhanced MRI and positron emission tomography of stereotactic laser-induced interstitial thermal therapy in cerebral gliomas. Neuroradiol [Suppl] 33:37–39Google Scholar
- 4.Hessel S, Frank F (1990) Technical prerequisites for the interstitial thermotherapy using the Nd:YAG laser. In: Optical Fibers in Medicine V, SPIE, pp 233–238Google Scholar
- 5.Jolesz FA, Bleier AR, Jakab P, Ruenzel PW, Huttl K, Jako GJ (1988) MR imaging of laser-tissue interactions. Radiol 168: 249–253Google Scholar
- 6.Lajac Y, Patrice T, Womballais F, Nogues B, Resche F (1987) Effects of 1.06 um wavelength laser radiation applied stereotactically to brain tissue. Laser Surg Med 3:45–51Google Scholar