Clinical use of the Laser-Speckle-Method for a Non-Contact Detection of skin Circulation in Patients with Diabetes Mellitus
In the clinical workaday routine, we find a lot of situations where a simple and non-invasive method for fast, quantitative measurement of the circulation without sideeffects is needed: Not only in terms of diabetic microangiopathy, what we investigated, but also in plastic and reconstructive surgery (e.g. perfusion of free flaps), in transplant surgery (e.g. quality of graft perfusion), in terms of arterial occlusive disease, secondary wound healing and during anesthesia, just to mention a few. Up to now, none of the clinical established methods for blood flow detection is able to fulfill the conditions mentioned above. Either they are indirect measurements only, like thermographia (Abendroth, 1987) or detection of the surface p02 (Kessler 1969), or they are not applicable in patients because of their side-effects, like fluorescent markers for intravital microscopy (Zimmerhackl, 1983) or radioactive microspheres (Buckberg, 1971). Even the Laser-Doppler-Method (Nilsson, 1980) has a severe disadvantage: the probe is attached to the skin and therefore disturbes microcirculation.
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