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Cardiac Muscle pp 195-221 | Cite as

Cardiac Muscle Cells in Culture

  • Enrico D. Canale
  • Gordon R. Campbell
  • Joseph J. Smolich
  • Julie H. Campbell
Part of the Handbook of Microscopic Anatomy book series (MIKROSKOPISCHEN, volume 2 / 7)

Abstract

Cardiac muscle has been grown in culture since 1910 when the independent spontaneous contraction of small clumps of tissue was observed (Burrows 1910, 1912). Until the 1950’s, most of the studies involved explant culture and the modification of nutrient medium to maintain the cells in a differentiated, contractile state (see Murray 1965). In 1955 Cavanaugh enzymatically dispersed cardiac muscle into single cells and systematically observed their behaviour.

Keywords

Purkinje Cell Adenylate Cyclase Cardiac Muscle Myocardial Cell Heart Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • Enrico D. Canale
    • 1
  • Gordon R. Campbell
    • 1
  • Joseph J. Smolich
    • 2
  • Julie H. Campbell
    • 2
  1. 1.Cardiovascular Research Unit, Department of AnatomyUniversity of MelbourneParkvilleAustralia
  2. 2.Baker Medical Research InstituteParhranAustralia

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