Abstract
The region of murine chromosome 1 surrounding the biochemical markers, Idh-1 and Pep-3 (band C) contains segments of homology with genes on human chromosomes 1, 2 and 18 (Lalley and McKusick 1985; Mock et al., in press). This 27 cM region of chromatin contains sites of endogenous proviral loci (Emy-16,17; Buchberg et al., 1986), an oncogene (bcl-2; Mock et al., 1987; in press) which, in man, is consistently rearranged in follicular lymphomas (Bakshi et al., 1985; Cleary and Sklar 1985; Tsujimoto et al., 1985), a cytolytic T-cell associated sequence (Ctla-4; Brunet et al., 1987) and genes involved in the serum complement system (Cfh and C4bp; Seldin in press; D’Eustachio et al. 1986), murine embryogenesis (En-1; Joyner et al. 1985), muscle development (Myl-1; Robert et al. 1984), the repair of chromatin breaks (Rep-1, Potter et al. in press) and the resistance/ susceptibility to Leishmania (Lsh, Bradley et al. 1979), Salmonella (Ity, Plant and Glynn 1976; Taylor and O’Brien 1982) and Mycobacterium (Bcg, Gros et al. 1981).
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© 1988 Springer-Verlag Berlin · Heidelberg
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Mock, B., Potter, M. (1988). A Molecular Characterization of BALB/c Congenic C.D2-Idh-1 b, Lsh r, Rep-1 b, Pep-3 b Mice. In: Mock, B., Potter, M. (eds) Genetics of Immunological Diseases. Current Topics in Microbiology and Immunology, vol 137. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-50059-6_44
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DOI: https://doi.org/10.1007/978-3-642-50059-6_44
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