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Ergebnisse der Physiologie Biologischen Chemie und Experimentellen Pharmakologie pp 299–430Cite as

The Mechanism of Synaptic Transmission

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Part of the book series: Ergebnisse der Physiologie Biologischen Chemie und Experimentellen Pharmakologie ((ERGEBPHYSIOL,volume 51))

Zusammenfassung

In the twenty five years since my previous review was published in the Ergebnisse der Physiologie (Eccles 1936), the subject of synaptic transmission has been transformed. The enormous advances in knowledge and understanding have been brought about largely as a result of the microtechniques: electron-microscopy; electrical investigations by microelectrodes, particularly with intracellular electrodes; and micro-injection procedures, both extracellular and intracellular. There is an excellent review of synaptic transmission immediately before the introduction of these microtechniques (Fešsard And Posternak 1950). Relatively few types of synaptic junctions have yet been subjected to intensive investigation by these new procedures; nevertheless one can have confidence that general principles of synaptic action are being established because there has been a remarkable uniformity of the essential features of synaptic actions for a wide variety of junctional regions in invertebrates as well as vertebrates.

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Authors and Affiliations

  1. Department of Physiology, John Curtin School of Medical Research, Australian National University, Canberra, Australia

    John C. Eccles

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  1. John C. Eccles
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Editors and Affiliations

  1. Göttingen, Deutschland

    K. Kramer

  2. Boston, USA

    O. Krayer

  3. Münster I. Westf., Deutschland

    E. Lehnartz

  4. Bern, Schweiz

    A. v. Muralt

  5. Heidelberg, Deutschland

    H. H. Weber

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© 1961 Springer-Verlag OHG / Berlin · Göttingen · Heidelberg

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Eccles, J.C. (1961). The Mechanism of Synaptic Transmission. In: Kramer, K., Krayer, O., Lehnartz, E., v. Muralt, A., Weber, H.H. (eds) Ergebnisse der Physiologie Biologischen Chemie und Experimentellen Pharmakologie. Ergebnisse der Physiologie Biologischen Chemie und Experimentellen Pharmakologie, vol 51. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-49946-3_8

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  • DOI: https://doi.org/10.1007/978-3-642-49946-3_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-49652-3

  • Online ISBN: 978-3-642-49946-3

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