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Festschrift zum 75. Geburtstag pp 29–38Cite as

Renal vascular changes produced by the mercurial diuretic salyrgan

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Abstract

It is generally stated that mercurial diuretics do not change the hemodynamics of the kidney1, 2. On the other hand, reductions in kidney volume, renal blood flow and glomerular filtration have been described by a number of independent investigators3, 4, 5, while Dicker 6 has shown that in rats salyrgan increases the diodrast and inulin clearances. A study of the available literature indicates that mercurials can produce several qualitatively and quantitatively different effects on the renal hemodynamics. In the present study an attempt will be made to characterize these mercurial-induced renal vascular changes in the dog and to elucidate the importance of these changes in the response of the kidney to these diuretics.

In honor of Professor Wolfgang Heubner on his 75th birthday.

Supported by a grant from the Hendricks Research Fund, Syracuse N. Y. and Ciba Pharmaceutical Company, Summit, New Jersey.

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Author information

Authors and Affiliations

  1. Dept. of Pharmacology, State University of New York at Syracuse, College of Medicine, USA

    Dr. Alfred Farah

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  1. Dr. Alfred Farah
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Editor information

Editors and Affiliations

  1. Freiburg/Br., Deutschland

    L. Heilmeyer

  2. Berlin, Deutschland

    H. Herken

  3. Göttingen, Deutschland

    L. Lendle

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© 1952 Springer-Verlag Berlin Heidelberg

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Farah, A. (1952). Renal vascular changes produced by the mercurial diuretic salyrgan. In: Heilmeyer, L., Herken, H., Lendle, L. (eds) Festschrift zum 75. Geburtstag. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-49902-9_5

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  • DOI: https://doi.org/10.1007/978-3-642-49902-9_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-49610-3

  • Online ISBN: 978-3-642-49902-9

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