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Abstract

The nucleus, both during interphase and mitosis, has come to be regarded as one of the most difficult of biological objects to study by methods of electron microscopy. Apart from the nuclear envelope there are few land marks and little evidence of order such as we find in collagen or muscle. What organization there may be is distributed in depth in the whole nucleus and so defies all but the most painstaking efforts in serial thin sectioning. It is not surprising, therefore, that the problem has proved discouraging except for the most determined and interested investigators. Of these we have a representative few on the program of this symposium and they will give you some measure of the progress that has been made to date. In view of the difficulties, their achievements must be regarded as impressive.

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References

  1. Allfrey, V. G., A. EMirsxyand SOsawa: J. gen. Physiol. 40, 451 (1957)

    Article  PubMed  CAS  Google Scholar 

  2. Proc. nat. Acad. Sci. (Wash.) 43, 821 (1957).

    Article  Google Scholar 

  3. Pelo, S. R., and A. Howard: Exp. Cell. Res. 10, 549 (1956).

    Article  Google Scholar 

  4. Brachet, J.: Biochemical Cytology. New York: Academic Press 1957.

    Google Scholar 

  5. Gay, H.: J. biophys. biochem. Cytol. 2 (suppl.), 407 (1956).

    Article  PubMed  CAS  Google Scholar 

  6. Ris, H.: J. biophys. biochem. Cytol. 2 (suppl.), 385 (1955).

    Article  Google Scholar 

  7. Chromosoma structure. A symposium on the chemical basis of heredity. W. D. MCELROY and B. GLASS, editors. Baltimore: Johns Hopkins Press 1957.

    Google Scholar 

  8. Porter,K. R.: J. Histochem. Cytochem.2, 346 (1954).

    Article  PubMed  CAS  Google Scholar 

  9. Watson, M. G.: J. biophys. biochem. Cytol. 1, 257 (1955).

    Article  PubMed  CAS  Google Scholar 

  10. Derobertis, E.: J. biophys. biochem. Cytol. 2, 785 (1956).

    Article  CAS  Google Scholar 

  11. Moses, M. J.: J. biophys. biochem. Cytol. 4, 633 (1958).

    Article  PubMed  CAS  Google Scholar 

  12. Gall, J. G.: Chromosomal differentiation. A symposium on the chemical basis of development. W. D. MCELROY and B. GLASS, editors. Baltimore: Johns Hopkins Press 1957.

    Google Scholar 

  13. Kaufmann, B. P., and D. N. DE: J. biophys. biochem. Cytol. 2, (suppl.), 419 (1956).

    Article  PubMed  Google Scholar 

  14. Pappas, G. D.: J. biophys. biochem. Cytol. 2, 221 (1956).

    Article  PubMed  CAS  Google Scholar 

  15. Watson, M.: J. biophys. biochem. Cytol. 3, 1017 (1957).

    Article  PubMed  CAS  Google Scholar 

  16. Watson, M. L.: J. biophys. biochem. Cytol. 4, 727 (1958).

    Article  PubMed  CAS  Google Scholar 

  17. Grasse, P. P., NCarassoet PFayard: Ann. sci. nat. Zool. et Biol. anim. 18, 339 (1956)

    Google Scholar 

  18. Nebel, B. R.: J. Hered. 48, 51 (1957).

    Google Scholar 

  19. Caspersson, T. O.: Cell growth and cell function. p. 103. New York: W. W. Norton & Co. 1950.

    Google Scholar 

  20. GoldsteinL.,and WPlaut: Proc. nat. Acad. Sci. (Wash.) 41, 874 (1955).

    Article  CAS  Google Scholar 

  21. EstablÉ, C., et J. Sotelo: Inst. Inv. Cien. Biol. Publ. 1, 105 (1951).

    Google Scholar 

  22. J.RSotelo: In: Fine structure of cells. p. 170. Groningen: Noordhoff Ltd. 1954.

    Google Scholar 

  23. Hooben, L. T.: Proc. roy. Soc. B. 91, 305 (1920).

    Article  Google Scholar 

  24. Zirkle, C.: Cytologia 2, 85 (1931).

    Article  Google Scholar 

  25. CravenJ., H. G. Dames and U. JMiles: Proc. roy. Soc. B 141, 190 (1952).

    Google Scholar 

  26. Thorell, B.: Acta med. stand. 117, 334 (1944).

    Article  CAS  Google Scholar 

  27. Lafontaine, J. G.: J. biophys. biochem. Cytol. 4, 777 (1958).

    Article  PubMed  CAS  Google Scholar 

  28. Sotelo, J. R., and K. R. Porter: J. biophys. biochem. Cytol. 5, 327 (1959).

    Article  PubMed  CAS  Google Scholar 

  29. MontroseJMoses: Patterns of organization in the fine structure of chromosomes 199

    Google Scholar 

  30. Mcclintocx, B.: Z. Zellforsch. 21, 294 (1934).

    Article  Google Scholar 

  31. BernhardW., ABauer, AGropp, FHaguenauet CHOberling: Exp. Cell Res. 9, 88 (1955).

    Article  PubMed  CAS  Google Scholar 

  32. Bahr, G. F., and W. Beermann: Exp. Cell Res. 6, 519 (1954).

    Article  PubMed  CAS  Google Scholar 

  33. Hartmann, J. F.: J. Comp. Neurol. 99, 201 (1953).

    Article  PubMed  CAS  Google Scholar 

  34. Shatkin, A. J., and E. L. Tatum: J. biophys. biochem. Cytol. (in press).

    Google Scholar 

  35. Bradfield, J. R. G.: Symp. Soc. Gen. Microbiol. 6, 296 (1956).

    Google Scholar 

  36. Rebhuhn, L. I.: J. biophys. biochem. Cytol. 2, 93 (1956).

    Article  Google Scholar 

  37. Palade, G. E.: J. biophys. biochem. Cytol. 1, 59 (1955).

    Article  PubMed  CAS  Google Scholar 

  38. Porter, K. R., and G. E. Palade • J biophys. biochem. Cytol. 3, 269 (1957).

    CAS  Google Scholar 

  39. Porter, K. R., and G. E. Palade In: Fine structure of cells. p. 236. Groningen: Noordhoff Ltd. 1954.

    Google Scholar 

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W. Bargmann G. Möllenstedt H. Niehrs D. Peters E. Ruska C. Wolpers

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© 1960 Springer-Verlag Berlin Heidelberg

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Porter, K.R. (1960). Problems in the study of nuclear fine structure. In: Bargmann, W., Möllenstedt, G., Niehrs, H., Peters, D., Ruska, E., Wolpers, C. (eds) Vierter Internationaler Kongress für Elektronenmikroskopie / Fourth International Conference on Electron Microscopy / Quatrième Congrès International de Microscopie Électronique. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-49764-3_37

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  • DOI: https://doi.org/10.1007/978-3-642-49764-3_37

  • Publisher Name: Springer, Berlin, Heidelberg

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