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Radioactive Isotopes in Immunology

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Radioactive Isotopes in Physiology Diagnostics and Therapy / Künstliche Radioaktive Isotope in Physiologie Diagnostik und Therapie

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Abstract

Immunological investigations in the broadest sense encompass a comprehensive area of endeavor. The present review will therefore not attempt to cover all of the areas, nor all that has been done with isotopes in any one immunological area. Rather the reviewer will attempt to show the use of radioisotopes in immunochemical and immunological areas with which he has been dealing, as well as other areas which have been actively investigated in the department with which he has been associated. Of the many review articles and published symposia dealing with the use and application of radioactive isotopes in immunological research the following are most comprehensive [Coons, Masouredis (1957), Hollaender, Bale (1957), Dixon]. The main areas to be covered (1953-July, 1958) are as follows: A) Procedures employed for radio labelling antigens and antibodies; B) Antigen-antibody reactions “in vitro”, C) Metabolism and fate of antigens and antibodies “in vivo”, including soluble antigen-antibody complexes; D) “In vitro” research on antibody synthesis; and E) Use of radioisotopes in such areas as “immunological unresponsiveness.”

These studies were supported by a grant (E-1268) from the National Institute of Allergy and Infectious Diseases N. I. H., and by a contract with the Office of the Surgeon General, Department of the Army, Contract No. 49-007-MD-248. Publication No. 198, Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh 13, Pennsylvania.

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References

Section A

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Section C

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Authors
  1. Paul H. Maurer
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H. Schwiegk F. Turba

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© 1961 Springer-Verlag Berlin · Göttingen · Heidelberg

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Maurer, P.H. (1961). Radioactive Isotopes in Immunology. In: Schwiegk, H., Turba, F. (eds) Radioactive Isotopes in Physiology Diagnostics and Therapy / Künstliche Radioaktive Isotope in Physiologie Diagnostik und Therapie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-49762-9_28

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  • DOI: https://doi.org/10.1007/978-3-642-49762-9_28

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