Abstract
The human pharmacology of hypotensive drugs is as complex as the experimental pharmacology (21, 28). Many drugs act by interfering with physiological mechanisms necessary for the maintenance of the arterial blood pressure, others by mechanisms that are unknown and can only be speculated about. The only way to test the usefulness of a drug in the treatment of high blood pressure is to try it in patients with hypertensive cardiovascular disease, because the complex clinical situation characteristic of such patients cannot be simulated in the laboratory.
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Sannerstedt, R., Schröder, G., Werkö, L. (1966). Haemodynamic analysis of some principles applied in the treatment of arterial hypertension. In: Gross, F. (eds) Antihypertensive Therapy. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-49737-7_17
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DOI: https://doi.org/10.1007/978-3-642-49737-7_17
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