Abstract
When an immunogen is injected into a higher organism, antibodies reacting specifically with that immunogen are produced. Since a vast number of antibody specificities exist, and since cogent evidence indicates that antibody specificity is determined by the primary structure of the antibody polypeptide chains, the question has to be asked of how antigen induces the structural genes coding for the “right” antibodies, and only these, to initiate protein synthesis.
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Rajewsky, K. (1969). The Significance of the Carrier Effect for the Induction of Antibodies. In: Westphal, O., Bock, HE., Grundmann, E. (eds) Current Problems in Immunology. Bayer-Symposium, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-49733-9_9
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DOI: https://doi.org/10.1007/978-3-642-49733-9_9
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