Skip to main content

Predicting delayed ischaemic deficit in subarachnoid haemorrhage

  • Conference paper
Proceedings of the XIV Symposium Neuroradiologicum

Summary

Fifty-nine patients with subarachnoid haemorrhage (SAH) were investigated noninvasively to identify those at risk of delayed cerebral ischaemia. Sixteen patients developed ischaemic deficit but there was no clear relationship with computed tomography blood load and distribution. Serial transcranial Doppler ultrasound (TCD) revealed significantly higher middle cerebral artery flow velocities in those with ischaemic deficit but highest values were often not seen until clinical deterioration had occurred. A rapid rise in flow velocity was observed in advance of clinical signs of ischaemia. Regional blood flow on HM-PAO single photon emission computed tomography (SPECT) in 10 patients with this rapid rise showed focal reduced perfusion in 8, 5 progressing to clinical deficit. A further patient developed infarction before SPECT was performed. Sequential TCD offers potential for identification of patients at risk of delayed ischaemic complications of SAH.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Fisher CM, Kistler JP, Davis JM (1980) Relation of cerebral vasospasm to subarachnoid haemorrhage visualized by computerized tomographic scanning. Neurosurgery 6:1–9

    Article  PubMed  CAS  Google Scholar 

  2. Gurusinghe NT, Richardson AE (1984) The value of computed tomography in aneurysmal subarachnoid hemorrhage. The concept of the CT score. J Neurosurg 60:763–770

    Article  PubMed  CAS  Google Scholar 

  3. Seiler RW, Grolimund P, Aaslid R, Huber P, Nornes H (1986) Cerebral vasospasm evaluated by transcranial ultrasound correlated with clinical grade and CT-visualized subarachnoid haemorrhage. J Neurosurg 64:594–600

    Article  PubMed  CAS  Google Scholar 

  4. Compton JS, Redmond S, Symon L (1983) Cerebral blood velocity in subarachnoid haemorrhage: a transcranial Doppler study. J Neurol Neurosurg Psychiatry 50:1499–1503

    Article  Google Scholar 

  5. Sekhar LM, Wechsler LR, Yonas H, Luyckx K, Obrist W (1988) Value of transcranial Doppler examination in the diagnosis of cerebral vasospasm after subarachnoid haemorrhage. Neurosurgery 22:813–821

    Article  PubMed  CAS  Google Scholar 

  6. Nakagawara JP, Nakamura J, Matsuzaki T, Takeda R, Wada K, Toshima M, Suematsu K (1987) Assessment of hemodynamic changes due to delayed cerebral vasospasm in subarachnoid hemorrhage using SPECT and 123I-IMP. In: Wilkins RH (ed) Cerebral vasospasm. Raven Press, New York, pp 79–85

    Google Scholar 

  7. Davis S, Andrews J, Lichtenstein M, Kaye K, Tress B, Rossiter S, Salehi N, Binns D (1990) A single-photon emission computed tomography study of hypoperfusion after subarachnoid hemorrhage. Stroke 21:252–259

    Article  PubMed  CAS  Google Scholar 

  8. Yonas H, Sekhard L, Johnson DW, Gur D (1989) Determination of irreversible ischaemia by xenon-enhanced computed tomographic monitoring of cerebral blood flow in patients with symptomatic vasospasm. Neurosurgery 24:368–372

    Article  PubMed  CAS  Google Scholar 

  9. Powers WJ, Grubb RL, Baker RP, Mintun MA, Raichle ME (1985) Regional cerebral blood flow and metabolism in reversible ischaemia due to vasospasm. Determination by positron emission tomography. J Neurosurg 62:539–546

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1991 Springer-Verlag

About this paper

Cite this paper

Grosset, D.G. et al. (1991). Predicting delayed ischaemic deficit in subarachnoid haemorrhage. In: du Boulay, G., Molyneux, A., Moseley, I. (eds) Proceedings of the XIV Symposium Neuroradiologicum. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-49329-4_16

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-49329-4_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-49331-7

  • Online ISBN: 978-3-642-49329-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics