Numerical Models of Oscillating Genetic Signals

Rörsch, A.; Groothuis, M. A. E.; Schepman, A. M. H.

doi:10.1007/978-3-642-49321-8_19

A. Rörsch²,
M. A. E. Groothuis² &
A. M. H. Schepman²

Part of the book series: Lecture Notes in Biomathematics ((LNBM,volume 29))

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Abstract

The study of genetic regulation is one of the most intriguing subjects in molecular biology. It is in itself of great importance to understand the regulatory mechanism of cell metabolism, of cyclic processes such as cell division and of cell differentiation. A new dimension was added recently when it was postulated that the evolution of multicellular organisms would be the evolution of genetic regulatory circuits, rather than the evolution of their individual cell constituents (King & Wilson, 1975). Thus in order to learn about the pathways of the evolution of higher organisms, we must learn more about the qualities of particular regulatory circuits and how Darwinian selection can act upon them.

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Authors and Affiliations

Department of Biochemistry, Leiden State University, The Netherlands
A. Rörsch, M. A. E. Groothuis & A. M. H. Schepman

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A. Rörsch
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M. A. E. Groothuis
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A. M. H. Schepman
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Department of Molecular Biology, Faculty of Sciences, University of Brussels, Rue des Chevaux, 67, B-1640, Rhode Saint Genèse, Belgium
René Thomas

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Rörsch, A., Groothuis, M.A.E., Schepman, A.M.H. (1979). Numerical Models of Oscillating Genetic Signals. In: Thomas, R. (eds) Kinetic Logic A Boolean Approach to the Analysis of Complex Regulatory Systems. Lecture Notes in Biomathematics, vol 29. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-49321-8_19

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DOI: https://doi.org/10.1007/978-3-642-49321-8_19
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-09556-9
Online ISBN: 978-3-642-49321-8
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