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Alterations in Immune Response to Experimental Murine Tumor-Associated Antigens Following Administration of BCG or Polysaccharide from Proteus vulgaris

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Investigation and Stimulation of Immunity in Cancer Patients

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 47))

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Abstract

It is now well established that most experimental tumors have associated antigens which are able to evoke immune reactions in syngeneic hosts [8, 18, 20]. Much experimental evidence has been accumulated indicating that the resulting antitumor immunity is weak [6, 13]. This led investigators to test adjuvant substances as nonspecific stimulators of the immune response to tumor-associated antigens. Various trials were made with numerous bacterial adjuvants and their effects on the development of transplanted tumors were studied.

This work was supported by a grant from INSERM.

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Authors and Affiliations

  1. Research Unit of Experimental Cancerology and Radiobiology, INSERM, Vandoeuvre-les-Nancy, France

    M. Donner & D. Vaillier

Authors
  1. M. Donner
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  2. D. Vaillier
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Editor information

Editors and Affiliations

  1. Institut de Cancérologie et d’Immunogénétique, Hôpital Paul-Brousse, F-94, Villejuif, France

    Georges Mathé (Professor) (Professor)

  2. Children’s Cancer Research Foundation, 35 Binney Street, 02115, Boston, MA, USA

    Roy Weiner M.D.

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© 1974 Springer-Verlag Berlin · Heidelberg

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Donner, M., Vaillier, D. (1974). Alterations in Immune Response to Experimental Murine Tumor-Associated Antigens Following Administration of BCG or Polysaccharide from Proteus vulgaris. In: Mathé, G., Weiner, R. (eds) Investigation and Stimulation of Immunity in Cancer Patients. Recent Results in Cancer Research, vol 47. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-49284-6_44

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  • DOI: https://doi.org/10.1007/978-3-642-49284-6_44

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-49286-0

  • Online ISBN: 978-3-642-49284-6

  • eBook Packages: Springer Book Archive

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