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Investigation and Stimulation of Immunity in Cancer Patients pp 149–165Cite as

Experimental Screening for “Systemic Adjuvants of Immunity” Applicable in Cancer Immunotherapy

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Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 47))

Abstract

The term “adjuvant” was introduced in immunology to designate an agent wich, when injected locally in a mixture with an antigen, was able to increase the immune (humoral) response to the antigen. Freund’s adjuvant [12] has been the most widely used. The stimulatory effect of such “adjuvants” on proliferation and phagocytic ativity of macrophages, as well as some undefined action on the physicochemical presentation of the antigenic sites of the immunizing substances have been the conventionally accepted hypotheses for their mechanisms of action [9, 12].

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Authors and Affiliations

  1. Institut de Cancérologie et d’Immunogénétique, Hôpital Paul-Brousse, Villejuif, France

    G. Mathé, M. Kamel, M. Dezfulian, O. Halle-Pannenko & C. Bourut

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  1. G. Mathé
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  2. M. Kamel
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  3. M. Dezfulian
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  4. O. Halle-Pannenko
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  5. C. Bourut
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Editors and Affiliations

  1. Institut de Cancérologie et d’Immunogénétique, Hôpital Paul-Brousse, F-94, Villejuif, France

    Georges Mathé (Professor) (Professor)

  2. Children’s Cancer Research Foundation, 35 Binney Street, 02115, Boston, MA, USA

    Roy Weiner M.D.

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© 1974 Springer-Verlag Berlin · Heidelberg

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Mathé, G., Kamel, M., Dezfulian, M., Halle-Pannenko, O., Bourut, C. (1974). Experimental Screening for “Systemic Adjuvants of Immunity” Applicable in Cancer Immunotherapy. In: Mathé, G., Weiner, R. (eds) Investigation and Stimulation of Immunity in Cancer Patients. Recent Results in Cancer Research, vol 47. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-49284-6_21

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  • DOI: https://doi.org/10.1007/978-3-642-49284-6_21

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-49286-0

  • Online ISBN: 978-3-642-49284-6

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