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Congenital Cancer and Congenital Abnormalities Associated with Cancer

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Hereditary Factors in Carcinoma

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Abstract

Malignancies present at birth pose a challenge to the geneticist, embryologist, epidemiologist, and oncologist. One of the most comprehensive reviews of the subject was that of Wells20 in 1940. His criterion for the definite occurrence of a congenital malignancy included the presence of the malignancy at birth and histologic confirmation during the neonatal period. He found about 250 reported congenital neoplasms in the world literature of which only 66 fulfilled this criterion. Sarcoma constituted nearly one-half of all the congenital malignancies while neuroblastoma comprised most of the other half. No convincingly proven cases of congenital carcinoma were found though several “possible” carcinomas were reported (particularly carcinoma of the liver). The proven cases included none of the common malignancies of man, namely lung, alimentary tract, and genitalia.

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Authors
  1. Henry T. Lynch M.D.
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© 1967 Springer-Verlag Berlin · Heidelberg

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Lynch, H.T. (1967). Congenital Cancer and Congenital Abnormalities Associated with Cancer. In: Hereditary Factors in Carcinoma. Recent Results in Cancer Research / Fortschritte der Krebsforschung / Progrès dans les recherches sur le cancer, vol 12. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-48252-6_8

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  • DOI: https://doi.org/10.1007/978-3-642-48252-6_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-48254-0

  • Online ISBN: 978-3-642-48252-6

  • eBook Packages: Springer Book Archive

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