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Genetic Aspects of Tumors of The Nervous System

  • Chapter
Hereditary Factors in Carcinoma

Abstract

In man’s quest to understand a group of diseases presently called neoplastic, genetic factors have been sought repeatedly. In current clinical neurologic experience, genetically predisposed tumors are interesting exceptions rather than the rule; the greatest percent of tumors of the nervous system do not appear to be of genetic origin. Yet these statements are made with the knowledge that very few neurologists, neurosurgeons or neuropathologists regularly make careful genetic studies in patients with neural tumors. Many retrospective analyses are based on old histories taken by others. (Some of the techniques necessary for valid clinical genetic significance include minimal subjective diagnoses, “blind” examinations of involved and control groups, and direct examinations by one investigator13).

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  1. John A. Aita Ph.D., M.D.
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Aita, J.A. (1967). Genetic Aspects of Tumors of The Nervous System. In: Hereditary Factors in Carcinoma. Recent Results in Cancer Research / Fortschritte der Krebsforschung / Progrès dans les recherches sur le cancer, vol 12. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-48252-6_6

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