Summary
After surgical resection of rectal carcinoma the R (residual tumor) classification and pTNM are independent prognostic factors. In patients with residual tumor, presence or absence of distant metastases influences prognosis. The pTNM-defined stage and substage is of prognostic influence for patients without residual tumor. In a study of 597 patients multivariate analysis was used to identify additional prognostic factors for individual substages. Similar studies on larger patient material are needed for further clarification of these prognostic factors.
Zusammenfassung
Nach operativer Entfernung von Rektumkarzinomen sind die R-(Residualtumor-)Klassifikation und pTNM als unabhängige Prognosefaktoren gesichert. Innerhalb der Patienten mit Residualtumor ist Vorhandensein oder Fehlen von Fernmetastasen, innerhalb der Patienten ohne Residualtumor das durch pTNM definierte Stadium und Substadium von Bedeutung. In einer Studie an 597 Patienten konnten durch multivariate Analyse in einzelnen Substadien zusätzliche unabhängige prognostische Faktoren identifiziert werden. Zur weiteren Klärung der Prognosefaktoren sind derartige Studien an größerem Material wünschenswert.
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Hermanek, P. et al. (1989). Tiefes Rektumkarzinom. In: Ungeheuer, E. (eds) Verhandlungen der Deutschen Gesellschaft für Chirurgie. Langenbecks Archiv für Chirurgie, vol 1989. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-48162-8_26
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