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Gerinnungsmanagement kardiovaskulärer Erkrankungen pp 1–13Cite as

Physiologische Aspekte der Gerinnungshemmung

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Zusammenfassung

Nach Verletzung der Gefäßwand durch Makro- oder Mikrotraumata führt ein gerichtetes Zusammenspiel aus Endothelzellen, Thrombozyten, Leukozyten, Gerinnungsfaktoren, Gerinnungsinhibitoren und Fibrinolysefaktoren zur Blutstillung und Reparatur der Verletzung.

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Literatur

  1. van den Belt AGM, Prins MR, Huisman MV, Hirsh J (1996) Familial Thrombophilia: a Review Analysis. Clin Appl Thrombosis/Hemostasis 2(4): 227–236

    Article  Google Scholar 

  2. Bertina RM, Koehleman BPC, Koster T et al. (1994) Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 369: 64–67

    Article  PubMed  CAS  Google Scholar 

  3. van der Born JG, Bots M, Haverkate F et al. (1996) Reduced response to activated protein C is associated with increased risk for cerebrovascular disease. Ann Intern Med 125: 265–269

    Google Scholar 

  4. van Boven HH, Poort SR, Bertina RM, Rosendaal FR (1997) Contribution of additional genetic risk factors in symptomatic antithrombin deficient individuals: FV 1691 A and F II 20210 A. Abstracts XVIth Congr. of the Int. Society on Thrombosis and Haemostasis, Florence, Italy, June 6–12, 1997. Thrombosis and Haemostasis Suppl 379

    Google Scholar 

  5. Dahlbäck B, Carlsson M, Svensson PJ (1993) Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C. Proc Natl Acad Sci USA 90: 1004–1008

    Article  PubMed  Google Scholar 

  6. Dahlbäck B, Hildebrand B (1994) Inherited resistance to activated protein C is corrected by anticoagulant cofactor activity found to be a property of factor V. Proc Natl Acad Sci USA 91: 1396–1400

    Article  PubMed  Google Scholar 

  7. Griffin JH, Evatt BL, Wideman C, Fernandez JA (1993) Anticoagulant protein C pathway defective in a majority of thrombophilic patients. Blood 32: 1989–1993

    Google Scholar 

  8. Halbmayer WM, Haushofer A, Schön R, Fischer M (1994) The prevalence of poor anticoagulant response to activated protein C (APC resistance) among patients suffering from stroke or venous thrombosis and among healthy subjects. Blood Coagul Fibrinol 5: 51–57

    Article  CAS  Google Scholar 

  9. den Heijer M, Koster T, Blom HJ, Bos GM J, Briet E, Reitsma PH, Vandenbrougke JP, Rosendaal FR (1996) Hyperhomocysteinemia as a risk factor for deep-vein thrombosis. N Engl J Med 334/12: 759–762

    Article  Google Scholar 

  10. Heimpel H, Hoelzer D, Lohmann HP, Scifried E (1996) Hämatologie in der Praxis. Gustav Fischer Verlag, Jena Stuttgart

    Google Scholar 

  11. Hillarp A, Dahlbäck B (1997) Activated protein C resistance. Vessels 3: 1,4–10

    Google Scholar 

  12. Kirchmaier CM, Schirmer A, Jablonka B, Meyer M, Just M, Breddin HK (1993) Prediction of bleeding risk in Glanzmann’s Thrombasthenia. Thromb Haemostas 69 (6): 921

    Google Scholar 

  13. Koster T, Rosendaal FR, de Ronde F, Briet E, Vandenbroucke JP, Bertina RM (1993) Venous thrombosis due to poor response to activated protein C: Leiden thrombophilia study. Lancet 342: 1503–1506

    Article  PubMed  CAS  Google Scholar 

  14. Lensen RPM, Rosendaal FR (1997) Factor V Leiden. Vessels 3: 11–15

    Google Scholar 

  15. Pötzsch B, Hund S, Müller-Berghaus G (1997) Dysfunctional thrombin: a new type of inherited thrombophilia? Abstracts XVIth Congr. of the Int. Society on Thrombosis and Haemostasis, Florence, Italy, June 6–12, 1997. Thrombosis and Haemostasis Suppl 180

    Google Scholar 

  16. Scifried E (1996) Erkrankungen des Gerinnungssystems. In: Classen M, Dierkesmann R, Heimpel H, Kalden JR, Koch KM, Meyer J, Spengel FA, Ziegler R (Hrsg) Rationelle Diagnostik und Therapie in der Inneren Medizin. Urban & Schwarzenberg Verlag.

    Google Scholar 

  17. Seligsohn U, Zivelin A (1997) Thrombophilia as a Multigenic Disorder. Thrombosis and Haemostasis 78(1): 297–301

    PubMed  CAS  Google Scholar 

  18. Svensson PJ, Dahlbäck B (1994) Resistance to activated protein C as a basis for venous thrombosis. N Engl J Med 330: 517–521

    Article  PubMed  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Institut für Transfusionsmedizin und Immunhämatologie, Blutspendedienst Hessen des Deutschen Roten Kreuzes gGmbH, Sandhofstraße 1, 60528, Frankfurt am Main, Deutschland

    Prof. Dr. E. Seifried

Authors
  1. Prof. Dr. E. Seifried
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Editor information

Editors and Affiliations

  1. Klinik am See, Seebad 84, D-15562, Rüdersdorf, Deutschland

    Heinz Völler

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© 1997 Dr. Dietrich Steinkopff Verlag, GmbH & Co. KG, Darmstadt

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Cite this paper

Seifried, E. (1997). Physiologische Aspekte der Gerinnungshemmung. In: Völler, H. (eds) Gerinnungsmanagement kardiovaskulärer Erkrankungen. Steinkopff. https://doi.org/10.1007/978-3-642-48052-2_1

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  • DOI: https://doi.org/10.1007/978-3-642-48052-2_1

  • Publisher Name: Steinkopff

  • Print ISBN: 978-3-7985-1092-0

  • Online ISBN: 978-3-642-48052-2

  • eBook Packages: Springer Book Archive

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