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Abstract

The development of the forearm technique over a decade ago has made it possible to study the dynamics of metabolic processes, particularly glucose assimilation, in human peripheral tissues in vivo under various physiological conditions. Sincle muscle, the main constituent of forearm tissues, comprises over half the body mass in the normal lean subject, its influence on the overall metabolic balance of the body must be considerable. Studies of glucose assimilation by muscles in normal, obese and diabetic subjects have revealed important differences between the groups and helped to elucidate the mechanism of action of a number of antidiabetic drugs.

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© 1971 Springer-Verlag Berlin Heidelberg

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Whichelow, M.J., Butterfield, W.J.H. (1971). Peripheral Glucose Uptake in Man in Diabetes and Obesity. In: Pfeiffer, E.F. (eds) Pathophysiologie und Klinik / Pathophysiology and Clinical Considerations. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-47669-3_9

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  • DOI: https://doi.org/10.1007/978-3-642-47669-3_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-47671-6

  • Online ISBN: 978-3-642-47669-3

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