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Pankreas

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Verhandlungen der Deutschen Gesellschaft für innere Medizin

Part of the book series: Verhandlungen der Deutschen Gesellschaft für innere Medizin ((VDGINNERE,volume 87))

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Zusammenfassung

Aus tierexperimentellen Arbeiten ist bekannt, daß sich die Enzymsekretion der Bauchspeicheldrüse an die in der Nahrung langfristig vorherrschende Nährstoffkomponente anpaßt. Bei kohlenhydratreicher Ernährung wurde ein Anstieg der Amylaseaktivität und bei eiweißreicher Kost eine Erhöhung der Aktivität proteolytischer Enzyme im Pankreassaft beobachtet. Zum Einfluß einer fettreichen Ernährung wurden widersprüchliche Befunde erhoben. Auf welchem Wege die Adaptation der Pankreasenzymsekretion an die Diät zustandekommt, ist bisher nicht bekannt. Neben Veränderungen im Pankreas selbst ist aufgrund neuerer Untersuchungen, in denen eine selektive Sekretion einzelner Pankreasenzyme beobachtet wurde, auch eine veränderte Pankreasstimulation als Ursache zu diskutieren. Es war deshalb das Ziel unserer Untersuchung festzustellen, welchen Einfluß Diäten mit extremer Nährstoffrelation auf die hormonale Stimulierbarkeit des Pankreas und auf seien Sekretionsantwort haben.

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Literatur

  1. Babson SR, Babson AL (1973) An improved amylase assay using dyed amylopectin. Clin Chim Acta 44: 193–197

    Article  PubMed  CAS  Google Scholar 

  2. Banauch D, Brummer W, Ebeling W, Metz H, Rindfrey H, Lang H, Leybold K, Rick W (1975) Eine Glucose-Dehydrogenase für die Glucose-Bestimmung in Körperflüssigkeiten. J Clin Chem Clin Biochem 13: 101–107

    CAS  Google Scholar 

  3. Kiehm TG, Anderson IW, Ward K (1976) Beneficial effects of a high carbohydrate, high fiber diet in hyperglycemic men. Am J Clin Nutr 29: 895–899

    PubMed  CAS  Google Scholar 

  4. Jenkins DJA, Goff VD, Leeds AR, Alberti KGMM (1976) Unabsorbable carbohydrates and diabetes: decreased post-prandial hyperglycemia. Lancet 2: 172–174

    Article  PubMed  CAS  Google Scholar 

  5. Holt S, Heading RC, Carter DC, Prescott LF, Tothill P (1979) Effect of gel fibre on gastric emptying and absorption of glucose and paracetamol. Lancet 1: 636–639

    Article  PubMed  CAS  Google Scholar 

  6. Liebow C, Rothman SS (1975) Science 189: 472–474

    Article  CAS  Google Scholar 

  7. Götze H, Rothman SS (1975) Nature 257: 607–609

    Article  PubMed  Google Scholar 

  8. Diamond JM (1978) Nature 271: 111–112

    Article  Google Scholar 

  9. Heinrich HC, Gabbe EE, Brüggmann J, Icagic F (1979) Klin Wochenschr 57: 1295–1297

    Article  PubMed  CAS  Google Scholar 

  10. Bieger W, Scheele G (1980) Anal Biochem 109: 222–230

    Article  PubMed  CAS  Google Scholar 

  11. Clemente F et al. (1971) Comparison des protéines de sucs pancréatiques humains normaux et pathologiques. Dosage des protéines sériques et mise en évidence d’une protéine particulière dans la pancréatite chronique calcifiante. Biochim Biophys Acta 251: 456–466

    Article  PubMed  CAS  Google Scholar 

  12. Clemente F et al. (1971) Albumin, IgG et IgA dans le suc pancréatique humain normal chez l’adulte. Clin Chim Acta 33: 317–324

    Article  PubMed  CAS  Google Scholar 

  13. Estevenon JP et al. (1975) Lactoferrin in the duodenal juice of patients with chronic calcifying pancreatitis. Scand J Gastroenterol 10: 327–330

    PubMed  CAS  Google Scholar 

  14. Fedail SS et al. (1979) Trypsin and lactoferrin levels in pure pancreatic juice in patients with pancreatic disease. Gut 20: 983–986

    Article  PubMed  CAS  Google Scholar 

  15. Tympner F, Gutmann W (1979) Laktoferrinkonzentration im reinen Pankreassekret bei chronischer Pankreatitis. Z Gastroenterol 12: 858–861

    Google Scholar 

  16. Adrian TE, Barnes AJ, Bloom SR (1979) Hypotrypsinaemia in diabetes mellitus. Clin Chim Acta 97: 213–216

    Article  PubMed  CAS  Google Scholar 

  17. Bartelheimer H, Ritter U (1960) Das exkretorische Pankreas bei Diabetikern. Med Klin 55: 700–703

    PubMed  CAS  Google Scholar 

  18. Chey WY, Shay H, Shuman CR (1963) External pancreatic secretion in diabetes mellitus. Ann Intern Med 59: 812–821

    Article  PubMed  CAS  Google Scholar 

  19. Creutzfeldt W (1964) Funktionsdiagnostik bei Erkrankungen des exokrinen Pankreas. Verh Dtsch Ges Inn Med 70: 781–801

    PubMed  CAS  Google Scholar 

  20. Dandona P, Elias E, Beckett AG (1978) Serum trypsin concentrations in diabetes mellitus. Br Med J 2: 1125

    Article  PubMed  CAS  Google Scholar 

  21. DiMagno EP, Go VLW, Summerskill WHJ (1973) Relations between pancreatic enzyme outputs and malabsorption in severe pancreatic insufficiency. N Engl J Med 288: 813–815

    Article  PubMed  CAS  Google Scholar 

  22. Domschke W, Tympner F, Domschke S, Demling L (1975) Exocrine pancreatic function in juvenile diabetics. Am J Dig Dis 20: 309–312

    Article  PubMed  CAS  Google Scholar 

  23. Dreiling DA (1951) Studies in pancreatic function. IV. The use of the secretin test in the diagnosis of tumors in and about the pancreas. Gastroenterology 18: 184–196

    PubMed  CAS  Google Scholar 

  24. Drewes VM (1969) Exocrine pancreatic function estimated after intra-duodenal and after oral stimulation, and exocrine pancreatic function in patients with newly discovered diabetes mellitus and in long-term diabetes. In: Gregor O, Riedel O (eds) Modern gastroenterology. Schattauer, Stuttgart New York, pp 1229–1231

    Google Scholar 

  25. Felber JP, Bambule-Dick J (1980) Radioimmunoassay of plasma trypsin in pancreatic diseases and in juvenile-onset diabetes. In: Podolsky S, Viswanathan M (eds) Secondary diabetes: The spectrum of the diabetic syndromes. Raven Press, New York, pp 191–196

    Google Scholar 

  26. Frier BM, Adrian TE, Saunders JHB, Bloom SR (1980) Serum trypsin concentration and pancreatic trypsin secretion in insulin-dependent diabetes mellitus. Clin Chim Acta 105: 297–300

    Article  PubMed  CAS  Google Scholar 

  27. Frier BM, Saunders JHB, Wormsley KG, Bouchier IAD (1976) Exocrine pancreatic function in juvenile-onset diabetes mellitus. Gut 17: 685–691

    Article  PubMed  CAS  Google Scholar 

  28. Gamble DR, Moffatt A, Marks V (1979) Serum immunoreactive trypsin concentrations in infectious and non-infectious illness and in juvenile diabetes. J Clin Pathol 32: 897–901

    Article  PubMed  CAS  Google Scholar 

  29. Kamaryt J, Stejskal J, Osickova L (1978) Urinary isoamylase in juvenile diabetics. J Clin Chem Clin Biochem 16: 539–541

    PubMed  CAS  Google Scholar 

  30. O’Donnell MD, FitzGerald O, McGeeney KF (1977) Differential serum amylase determination by use of an inhibitor, and design of a routine procedure. Clin Chem 23: 560–566

    PubMed  Google Scholar 

  31. Palla JC, Ben Abdeljlil A, Desnuelle P (1968) Action de l’insulin sur la biosynthèse de l’amylase et de quelques autres enzymes du pancréas de rat. Biochim Biophys Acta 158: 25

    Article  PubMed  CAS  Google Scholar 

  32. Pollard HM, Miller L, Brewer WA (1943) The external secretion of the pancreas and diabetes mellitus. Am J Dig Dis 10: 20–23

    Article  CAS  Google Scholar 

  33. Ritter U (1965) Die exkretorische Pankreassekretion bei Diabetes mellitus. Dtsch Med Wochenschr 90: 1063–1064

    Article  PubMed  CAS  Google Scholar 

  34. Skrha J, Stepan J, Havranek T, Skrha F, Herfort K, Sramkova J, Pay J (1981) Isoamylases in diabetes mellitus. Diabetologia 20: 129–133

    Article  PubMed  CAS  Google Scholar 

  35. Vacca JB, Henke WJ, Knight WA (1964) The exocrine pancreas in diabetes mellitus. Ann Intern Med 61: 242–247

    Article  PubMed  CAS  Google Scholar 

  36. Yamagata S, Goto Y, Takebe T, Koizumi H (1969) Exocrine and endocrine function of the pancreas in diabetes mellitus and chronic pancreatitis. In: Gregor O, Riedel O (eds) Modern gastroenterology. Schattauer, Stuttgart New York, pp 1298–1300

    Google Scholar 

  37. Arnold R, Fuchs K et al. (1974) Zur Morphologie, Klinik, Diagnostik und Therapie des Zollinger-Ellison-Syndroms. Dtsch Med Wochenschr 99: 607–616

    Google Scholar 

  38. Burcharth F, Dage JG et al. (1979) Localization of gastrinomas by transhepatic portal catheterication and gastrin assay. Gastroenterology 77: 444–450

    PubMed  CAS  Google Scholar 

  39. Creuzfeldt W, Arnold R (1979) Endokrine Tumoren des Pankreas. Internist 20: 382–391

    Google Scholar 

  40. Fox PS, Hofmann JW et al. (1974) Surgical management of the Zollinger-Ellison syndrome. Surg Clin North Am 54: 395–407

    PubMed  CAS  Google Scholar 

  41. Fox PS et al. (1974) The influence of total gastrectomy on survival in malignant Zollinger-Ellison tumors. Ann Surg 180: 558–566

    Article  PubMed  CAS  Google Scholar 

  42. Hausamen TU et al. (1977) Behandlung peptischer Ulcera beim Zollinger-Ellison-Syndrom mit Histamin-H2-Rezeptor-Antagonisten. Dtsch Med Wochenschr 102: 1709–1712

    Article  PubMed  CAS  Google Scholar 

  43. McCarthy DM (1980) The place of surgery in the Zollinger-Ellison syndrome. N Engl J Med 302: 1344–1347

    Article  PubMed  CAS  Google Scholar 

  44. McGuigan JE, Wolfe MM (1980) Secretin injection test in the diagnosis of gastrinoma. Gastroenterology 79: 1324–1331

    PubMed  CAS  Google Scholar 

  45. Mihas AA et al. (1978) Calcium and secretin as provocative stimuli in the Zollinger-Ellison syndrome. Digestion 17: 1–10

    Article  PubMed  CAS  Google Scholar 

  46. Mignon M et al. (1980) Interest of a combined anti secretory treatment, cimetidine and pirencepin in the management of severe forms of Zollinger-Ellison syndroms. Digestion 20: 56–61

    Article  PubMed  CAS  Google Scholar 

  47. Stage JG, Stadil F (1979) The clinical diagnosis of the Zollinger-Ellison syndrome. Scand J Gastroenterol [Suppl 53] 14: 79–91

    Article  Google Scholar 

  48. Stage JG et al. (1978) Secretin and the Zollinger-Ellison syndrome: reliability of secretin tests and pathogenetic rule of secretin. Scand J Gastroenterol 13: 501–511

    Article  PubMed  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Med. Univ.-Klinik, Würzburg, Deutschland

    H. Sommer & H. Kasper

  2. 2.Med Klinik rechts der Isar der TU, München, Deutschland

    W. E. Hansen & G. Schulz

  3. Med. Univ.-Klinik, Deutschland

    G. Rohr

  4. Inst. für Anatomie und ZeltbiologieMarburg, Deutschland

    H. F. Kern

  5. Rockefeller Univ, New York, USA

    G. A. Scheele

  6. 5. Med. Abt., Krankenhaus, München-Schwabing, Deutschland

    J. Lohse & H. Kaess

  7. Med. Univ.-Klinik, Göttingen, Deutschland

    P. G. Lankisch, G. Manthey, J. Otto & H. Koop

  8. Fachklinik für Diabetes und Stoffwechselkrankh., Bad Lauterberg, Deutschland

    B. Willms

  9. Med. Poliklinik, Univ, Heidelberg, Deutschland

    G. E. Feurle, G. Wenzel-Herzer & V. Helmstaedter

  10. Zentrum der Chirurgie Univ, Frankfurt, Deutschland

    I. Klempa

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  1. H. Sommer
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K. Miehlke

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© 1981 Springer-Verlag Berlin Heidelberg

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Sommer, H. et al. (1981). Pankreas. In: Miehlke, K. (eds) Verhandlungen der Deutschen Gesellschaft für innere Medizin. Verhandlungen der Deutschen Gesellschaft für innere Medizin, vol 87. J.F. Bergmann-Verlag, Munich. https://doi.org/10.1007/978-3-642-47092-9_18

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  • DOI: https://doi.org/10.1007/978-3-642-47092-9_18

  • Publisher Name: J.F. Bergmann-Verlag, Munich

  • Print ISBN: 978-3-8070-0327-6

  • Online ISBN: 978-3-642-47092-9

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