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The Jukes-Cantor Transformation and Additivity of Estimated Genetic Distances

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Analyzing and Modeling Data and Knowledge

Abstract

We give a simple derivation for the Jukes-Cantor transformation. The importance of the transformation with respect to distance-based tree constructing methods is demonstrated. We show that it is not justified to expect that the transformation improves the additivity of the estimated distance if non-additivity is measured by the degree of violation of the equation in the four-point condition. Finally, some effects of model violation are discussed.

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© 1992 Springer-Verlag Berlin · Heidelberg

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Vach, W. (1992). The Jukes-Cantor Transformation and Additivity of Estimated Genetic Distances. In: Schader, M. (eds) Analyzing and Modeling Data and Knowledge. Studies in Classification, Data Analysis, and Knowledge Organization. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-46757-8_15

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  • DOI: https://doi.org/10.1007/978-3-642-46757-8_15

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-54708-2

  • Online ISBN: 978-3-642-46757-8

  • eBook Packages: Springer Book Archive

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