Abstract
Specific hyposensitization is the only causal therapy for type I hypersensitivity reactions besides allergen avoidance. Several immunologic changes are correlated with the efficacy of this treatment. They include reduced serum levels of allergen-specific IgE and a rise of allergen specific IgG antibodies, a diminished seasonal rise of pollen specific serum-IgE, a decrease in the proliferative response to stimulation with allergen of peripheral blood mononuclear cells (PBMC), and a reduced histamine release from basophils (summarized in [1]). Despite these observations, however, the working mechanisms of hyposensitization remain ill defined.
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© 1991 Springer-Verlag Berlin Heidelberg
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Prinz, J.C., Rieber, E.P., Ring, J. (1991). Loss of Fc ε R2/CD23 Expression on T and B Lymphocytes During Rush Hyposensitization. In: Ring, J., Przybilla, B. (eds) New Trends in Allergy III. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-46717-2_13
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DOI: https://doi.org/10.1007/978-3-642-46717-2_13
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